SCHEMBL14010389

SCHEMBL14010389

C=CC(=O)OCOc1ccc(-c2ccc(CCC)cc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
THRB P10828 7/20 0.64
ALDH1A1 P00352 1/20 0.45
ACACB O00763 1/20 0.42
ACACA Q13085 1/20 0.42
HPGD P15428 1/20 0.41
TSHR P16473 1/20 0.41
LMNA P02545 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
MCL1 Q07820 1/20 0.40
MAPT P10636 2/20 0.39
THRA P10827 2/20 0.39
FFAR1 O14842 1/20 0.39
PSMB5 P28074 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
KMT2A Q03164 2/20 0.38
NPC1 O15118 1/20 0.38
HRH3 Q9Y5N1 1/20 0.38
MEN1 O00255 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27883615 0.96 THRB (0.69) THRBALDH1A1HPGDTSHRLMNA
SCHEMBL14010397 0.92 THRB (0.60) THRBALDH1A1HPGDTSHRMAPT
SCHEMBL14010347 0.91 THRB (0.67) THRBALDH1A1HPGDTSHRLMNA
SCHEMBL16657527 0.91 THRB (0.60) THRBALDH1A1LMNAMAPTTHRA
SCHEMBL14088484 0.90 THRB (0.65) THRBALDH1A1LMNAMAPTTHRA
SCHEMBL23552995 0.89 THRB (0.64) THRBALDH1A1ACACBACACAHPGD
SCHEMBL21127912 0.89 THRB (0.64) THRBALDH1A1ACACBACACAHPGD
SCHEMBL14010392 0.89 THRB (0.48) THRBALDH1A1HPGDTSHRLMNA
SCHEMBL11917942 0.87 THRB (0.53) THRBALDH1A1HPGDTSHRL3MBTL1
SCHEMBL14010349 0.86 THRB (0.64) THRBALDH1A1LMNAMAPTTHRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9388259-B2 Photosensitive polymer and photoalignable phase difference film JNC CORPORATION (JP) 2016-07-12 US disclosed
US-20140225047-A1 PHOTOSENSITIVE POLYMER AND PHOTOALIGNABLE PHASE DIFFERENCE FILM JNC PETROCHEMICAL CORPORATION (JP) 2014-08-14 US disclosed
US-7449223-B2 containing an additive that improves the level of defects in the vicinity of the air interface for an optically anisotropic medium that exhibits either tilted alignment or horizontal alignment DAINIPPON INK AND CHEMICALS, INC. (JP) 2008-11-11 US disclosed
US-20070170394-A1 Polymerizable liquid crystal composition and optically anisotropic medium DAINIPPON INK AND CHEMICALS, INC. (JP) 2007-07-26 US disclosed