SCHEMBL14010397

SCHEMBL14010397

C=CC(=O)OCOc1ccc(-c2ccc(CCCC)cc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
THRB P10828 9/20 0.60
THRA P10827 6/20 0.50
RARB P10826 6/20 0.48
HPGD P15428 1/20 0.46
TSHR P16473 1/20 0.46
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
ALDH1A1 P00352 1/20 0.43
RARA P10276 1/20 0.43
MAPT P10636 1/20 0.43
MTOR P42345 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14010347 0.96 THRB (0.67) THRBTHRARARBHPGDTSHR
SCHEMBL14088484 0.95 THRB (0.65) THRBTHRARARBMEN1KMT2A
SCHEMBL14010389 0.92 THRB (0.64) THRBTHRAHPGDTSHRMEN1
SCHEMBL14010395 0.89 TSHR (0.56) THRBRARBHPGDTSHR
SCHEMBL12154170 0.88 THRB (0.62) THRBTHRARARBMEN1KMT2A
SCHEMBL27883615 0.88 THRB (0.69) THRBTHRAHPGDTSHRMEN1
SCHEMBL14010357 0.87 THRB (0.61) THRBTHRAHPGDTSHRMEN1
SCHEMBL14010388 0.86 RARB (0.56) THRBRARBHPGDTSHR
SCHEMBL14010392 0.86 THRB (0.48) THRBHPGDTSHRKMT2AALDH1A1
SCHEMBL16230828 0.85 RARB (0.58) THRBRARBHPGDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7449223-B2 containing an additive that improves the level of defects in the vicinity of the air interface for an optically anisotropic medium that exhibits either tilted alignment or horizontal alignment DAINIPPON INK AND CHEMICALS, INC. (JP) 2008-11-11 US disclosed
US-20070170394-A1 Polymerizable liquid crystal composition and optically anisotropic medium DAINIPPON INK AND CHEMICALS, INC. (JP) 2007-07-26 US disclosed