Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.42 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propionic Acid SCHEMBL5936395 | 0.82 | TSHR (0.48) | TSHRFFAR1ACMSDPDK1PDK2 | |
| SCHEMBL13554933 | 0.80 | ENPP2 (0.44) | TSHRACMSDALDH1A1PDK1PDK2 | |
| Malonic Acid SCHEMBL27771971 | 0.79 | NPC1 (0.50) | FFAR1ALDH1A1SMN1; SMN2 | |
| Benzylamine SCHEMBL28177368 | 0.78 | CYP2D6 (0.56) | TSHRALDH1A1SMN1; SMN2SLC7A5AKR1B1 | |
| SCHEMBL1401775 | 0.78 | AKR1B1 (0.60) | TSHRFFAR1ACMSDALDH1A1ENPP2 | |
| SCHEMBL19501287 | 0.77 | ALDH1A1 (0.62) | FFAR1ACMSDALDH1A1PDK1PDK2 | |
| Acetoacetic Acid SCHEMBL7556350 | 0.76 | HPGD (0.44) | FFAR1ALDH1A1MTNR1BAKR1B1 | |
| Acetoacetic Acid SCHEMBL28221327 | 0.76 | KDM4E (0.50) | ALDH1A1MTNR1B | |
| SCHEMBL123838 | 0.76 | TSHR (0.61) | TSHRACMSDENPP2PRSS1PRSS2 | |
| SCHEMBL29675845 | 0.76 | NPSR1 (0.50) | ALDH1A1MTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8609131-B2 | Absorbent dressing comprising hydrophilic polymer prepared via Michael reaction | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-12-17 | — | — | US | disclosed |
| EP-1855730-B1 | ABSORBENT DRESSING COMPRISING HYDROPHILIC POLYMER | 3M INNOVATIVE PROPERTIES CO (US) | 2013-12-11 | — | — | EP | disclosed |
| US-7932325-B2 | Azlactone telechelic polymer | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-04-26 | — | — | US | disclosed |
| EP-1819737-B1 | PHOTOCURABLE MICHAEL ADDITION POLYMERS | 3M INNOVATIVE PROPERTIES CO (US) | 2011-03-30 | — | — | EP | disclosed |
| EP-1805237-B1 | AZLACTONE TELECHELIC POLYMER | 3M INNOVATIVE PROPERTIES CO (US) | 2011-03-02 | — | — | EP | disclosed |
| EP-1841807-B1 | CROSSLINKABLE HYDROPHILIC MATERIALS FROM POLYMERS HAVING PENDENT MICHAEL DONOR GROUPS | 3M INNOVATIVE PROPERTIES CO (US) | 2010-04-07 | — | — | EP | disclosed |
| US-20100076169-A1 | AZLACTONE TELECHELIC POLYMER | 3M INNOVATIVE PROPERTIES COMPANY | 2010-03-25 | — | — | US | disclosed |
| US-7649054-B2 | Protective coating; curable; Michael donor, a polyacryl component, and ethylenically unsaturated monomer having a reactive azlactone functional group | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2010-01-19 | — | — | US | disclosed |
| US-7642321-B2 | Ring-opened azlactone telechelic polymer | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2010-01-05 | — | — | US | disclosed |
| US-7473719-B2 | Crosslinkable hydrophilic materials from polymers having pendent Michael donor groups | 3M INNOVATIVE PROPERTIES (US) | 2009-01-06 | — | — | US | disclosed |
| WO-2006081079-A1 | CROSSLINKABLE HYDROPHILIC MATERIALS FROM POLYMERS HAVING PENDENT MICHAEL DONOR GROUPS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2006-08-03 | — | — | WO | disclosed |
| WO-2006081090-A2 | ABSORBENT DRESSING COMPRISING HYDROPHILIC POLYMER | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2006-08-03 | — | — | WO | disclosed |
| US-20060167180-A1 | Crosslinkable hydrophilic materials from polymers having pendent Michael donor groups | 3M INNOVATIVE PROPERTIES COMPANY | 2006-07-27 | — | — | US | disclosed |
| US-20060165762-A1 | Absorbent dressing comprising hydrophilic polymer | 3M INNOVATIVE PROPERTIES COMPANY | 2006-07-27 | — | — | US | disclosed |
| WO-2006065369-A2 | PHOTOCURABLE MICHAEL ADDITION POLYMERS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2006-06-22 | — | — | WO | disclosed |
| US-20060128825-A1 | Photocurable michael addition polymers | 3M INNOVATIVE PROPERTIES COMPANY | 2006-06-15 | — | — | US | disclosed |
| WO-2006039064-A1 | AZLACTONE TELECHELIC POLYMER | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2006-04-13 | — | — | WO | disclosed |
| WO-2006039141-A1 | RING-OPENED AZLACTONE TELECHELIC POLYMER | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2006-04-13 | — | — | WO | disclosed |
| US-20060074196-A1 | Azlactone telechelic polymer | 3M INNOVATIVE PROPERTIES COMPANY | 2006-04-06 | — | — | US | disclosed |
| US-20060074211-A1 | Coated on a substrate and at least partially polymerized to form a protective coating.; composite article; using a mono-ethylenically unsaturated monomer to regulate and control the molecular weight of the resulting polymers | 3M INNOVATIVE PROPERTIES COMPANY | 2006-04-06 | — | — | US | disclosed |