Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 7/20 | 0.44 |
| ▸ | F13A1 | P00488 | 4/20 | 0.44 |
| ▸ | TGM1 | P22735 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | HPN | P05981 | 1/20 | 0.40 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TGM6 | O95932 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL146869 | 0.81 | ALDH1A1 (0.49) | TGM2F13A1TGM1MEN1KMT2A | |
| SCHEMBL144613 | 0.79 | P2RX7 (0.41) | TGM2F13A1TGM1MEN1KMT2A | |
| SCHEMBL141505 | 0.76 | SYK (0.45) | TGM2F13A1TGM1KMT2ACTSL | |
| SCHEMBL140115 | 0.75 | ALDH1A1 (0.43) | TGM2F13A1TGM1MEN1KMT2A | |
| SCHEMBL1319262 | 0.74 | GAA (0.42) | GAAPKM | |
| SCHEMBL17329132 | 0.73 | ALDH1A1 (0.56) | TGM2F13A1TGM1MEN1KMT2A | |
| SCHEMBL15944722 | 0.73 | ALDH1A1 (0.56) | TGM2F13A1TGM1MEN1KMT2A | |
| SCHEMBL82964 | 0.73 | GAA (0.42) | ALDH1A1GAAPKM | |
| SCHEMBL15204759 | 0.73 | ALDH1A1 (0.49) | TGM2F13A1TGM1MEN1KMT2A | |
| SCHEMBL15204757 | 0.73 | ALDH1A1 (0.49) | TGM2F13A1TGM1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120058989-A1 | ANTIBACTERIAL FLUOROQUINOLONE ANALOGS | ACHAOGEN, INC. (US) | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120058989-A1 | ANTIBACTERIAL FLUOROQUINOLONE ANALOGS | RECQL, BLVRB, NQO2 | TGM2 2626/4885F13A1 3320/4885TGM1 1446/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.