Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.33 |
| ▸ | GGT1 | P19440 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | CPT2 | P23786 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL27870914 | 0.97 | HMGCR (0.35) | HMGCRCHRM1TBXA2RADRA1AKDM4E | |
| Oxalic Acid SCHEMBL15331129 | 0.97 | HMGCR (0.35) | HMGCRCHRM1TBXA2RADRA1AKDM4E | |
| SCHEMBL690783 | 0.92 | — | — | |
| SCHEMBL27722359 | 0.89 | — | — | |
| Acrylic Acid SCHEMBL27474257 | 0.81 | LMNA (0.43) | HMGCRCHRM1TBXA2RADRA1AKDM4E | |
| Oxalic Acid SCHEMBL27994653 | 0.80 | CA4 (0.35) | ALDH1A1 | |
| Deanol SCHEMBL11871103 | 0.75 | MEN1 (0.37) | HMGCRCHRM1TBXA2RADRA1AKDM4E | |
| Oxalic Acid SCHEMBL10594364 | 0.75 | ALDH1A1 (0.41) | HMGCRCHRM1TBXA2RADRA1AKDM4E | |
| SCHEMBL84219 | 0.75 | — | — | |
| SCHEMBL1986433 | 0.74 | GGT1 (0.46) | HMGCRCHRM1TBXA2RADRA1AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113598170-B | Medicament composition containing phenamacril and copper diacetonamine oxalate | 信阳农林学院 | 2022-04-22 | — | — | CN | claimed |
| CN-113598170-A | Medicament composition containing phenamacril and copper diacetonamine oxalate | 信阳农林学院 | 2021-11-05 | — | — | CN | claimed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| CN-113598174-B | Pharmaceutical composition containing validamycin and copper diacetonamine oxalate | 信阳农林学院 | 2022-04-22 | — | — | CN | disclosed |
| CN-113598170-B | Medicament composition containing phenamacril and copper diacetonamine oxalate | 信阳农林学院 | 2022-04-22 | — | — | CN | disclosed |
| CN-113598170-B | Medicament composition containing phenamacril and copper diacetonamine oxalate | 信阳农林学院 | 2022-04-22 | — | — | CN | disclosed |
| CN-113207898-B | Bactericide composition for preventing and treating wheat scab | 信阳农林学院 | 2021-12-24 | — | — | CN | disclosed |
| CN-113598170-A | Medicament composition containing phenamacril and copper diacetonamine oxalate | 信阳农林学院 | 2021-11-05 | — | — | CN | disclosed |
| CN-113598174-A | Pharmaceutical composition containing validamycin and copper diacetonamine oxalate | 信阳农林学院 | 2021-11-05 | — | — | CN | disclosed |
| CN-113598170-A | Medicament composition containing phenamacril and copper diacetonamine oxalate | 信阳农林学院 | 2021-11-05 | — | — | CN | disclosed |
| CN-113243383-A | Selenium-enriched intensified fertilizer for cultivating selenium-enriched watermelons | 广西壮族自治区农业科学院 | 2021-08-13 | — | — | CN | disclosed |
| US-5977178-A | Compounds with growth hormone releasing properties | NOVO NORDISK A/S (DK) | 1999-11-02 | — | — | US | disclosed |
| US-5919777-A | PIPERAZINE DERIVATIVES USEFUL FOR TREATING MEDICAL DISORDERS RESULTING FROM A GROWTH HORMONE DEFIENCY | NOVO NORDISK A/S (DK) | 1999-07-06 | — | — | US | disclosed |
| EP-0907643-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1999-04-14 | — | — | EP | disclosed |
| CN-1211991-A | Compounds with growth hormone releasing properties | NOVO NORDISK AS (DK) | 1999-03-24 | — | — | CN | disclosed |
| WO-1998046631-A1 | COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC MACROCYCLES AND PROCESSES THEREFOR | ELI LILLY AND COMPANY (US) | 1998-10-22 | — | — | WO | disclosed |
| WO-1998046786-A1 | COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC AMINOTHIOETHER ACIDS | ELI LILLY AND COMPANY (US) | 1998-10-22 | — | — | WO | disclosed |
| EP-0869974-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997040023-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1997-10-30 | — | — | WO | disclosed |
| WO-1997023508-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1997-07-03 | — | — | WO | disclosed |