Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.63 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | PTPN7 | P35236 | 3/20 | 0.56 |
| ▸ | HMGCR | P04035 | 3/20 | 0.56 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.52 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.52 |
| ▸ | PPARG | P37231 | 5/20 | 0.50 |
| ▸ | PPARD | Q03181 | 5/20 | 0.50 |
| ▸ | PPARA | Q07869 | 5/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16701316 | 1.00 | TSHR (0.63) | TSHRLMNANFKB1PMP22HSD17B10 | |
| SCHEMBL970516 | 1.00 | TSHR (0.63) | TSHRLMNANFKB1PMP22HSD17B10 | |
| SCHEMBL7382880 | 1.00 | TSHR (0.63) | TSHRLMNANFKB1PMP22HSD17B10 | |
| SCHEMBL6539108 | 1.00 | TSHR (0.63) | TSHRLMNANFKB1PMP22HSD17B10 | |
| SCHEMBL3972155 | 1.00 | TSHR (0.63) | TSHRLMNANFKB1PMP22HSD17B10 | |
| SCHEMBL3980051 | 1.00 | TSHR (0.63) | TSHRLMNANFKB1PMP22HSD17B10 | |
| SCHEMBL1702085 | 1.00 | TSHR (0.63) | TSHRLMNANFKB1PMP22HSD17B10 | |
| SCHEMBL374773 | 1.00 | TSHR (0.63) | TSHRLMNANFKB1PMP22HSD17B10 | |
| SCHEMBL1654498 | 1.00 | TSHR (0.63) | TSHRLMNANFKB1PMP22HSD17B10 | |
| SCHEMBL7292218 | 1.00 | TSHR (0.63) | TSHRLMNANFKB1PMP22HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 256 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230102146-A1 | MULTI-TARGET TYROSINE KINASE INHIBITOR | SHENZHEN NEPTUNUS PHARMACEUTICAL RESEARCH INSTITUTE CO., LTD. (CN) | 2023-03-30 | — | — | US | claimed |
| EP-4108666-A1 | MULTI-TARGET TYROSINE KINASE INHIBITOR | Shenzhen Neptunus Pharmaceutical Research Institute Co., Ltd. (CN) | 2022-12-28 | — | — | EP | claimed |
| CN-113336768-B | Multi-target tyrosine kinase inhibitor | 深圳海王医药科技研究院有限公司 | 2022-08-19 | — | — | CN | claimed |
| CN-113336768-A | Multi-target tyrosine kinase inhibitor | 深圳海王医药科技研究院有限公司 | 2021-09-03 | — | — | CN | claimed |
| US-20230103337-A1 | MEDICINE FOR IMPROVING STATE OF PREGNANCY, AND USE THEREOF | Yamaguchi, Koushi (JP) | 2023-04-06 | — | — | US | disclosed |
| US-20230102146-A1 | MULTI-TARGET TYROSINE KINASE INHIBITOR | SHENZHEN NEPTUNUS PHARMACEUTICAL RESEARCH INSTITUTE CO., LTD. (CN) | 2023-03-30 | — | — | US | disclosed |
| US-11541040-B2 | Medicine for improving state of pregnancy, and use thereof | Yamaguchi, Kouchi (JP) | 2023-01-03 | — | — | US | disclosed |
| EP-4108666-A1 | MULTI-TARGET TYROSINE KINASE INHIBITOR | Shenzhen Neptunus Pharmaceutical Research Institute Co., Ltd. (CN) | 2022-12-28 | — | — | EP | disclosed |
| CN-113336768-B | Multi-target tyrosine kinase inhibitor | 深圳海王医药科技研究院有限公司 | 2022-08-19 | — | — | CN | disclosed |
| EP-3977995-A1 | TACROLIMUS FOR AMELIORATING PREGNANCY CONDITIONS | Yamaguchi, Koushi (JP) | 2022-04-06 | — | — | EP | disclosed |
| EP-3900729-A1 | AGENT FOR IMPROVING INFERTILITY, RECURRENT MISCARRIAGE, AND STATE OF PREGNANCY | Yamaguchi, Koushi (JP) | 2021-10-27 | — | — | EP | disclosed |
| EP-3246036-B1 | MEDICINE FOR IMPROVING PREGNANCY-INDUCED HYPERTENSION SYNDROME | YAMAGUCHI KOUSHI (JP) | 2021-10-13 | — | — | EP | disclosed |
| US-4894366-A | Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1990-01-16 | — | — | US | disclosed |
| CN-1037155-A | Amino acid derivative | MERCK PATENT GMBH (DE) | 1989-11-15 | — | — | CN | disclosed |
| EP-0339483-A2 | Renin inhbiting amino-acid derivatives | MERCK PATENT GmbH (DE) | 1989-11-02 | — | — | EP | disclosed |
| EP-0337334-A2 | Renin-inhibiting amino acid derivatives | MERCK PATENT GmbH (DE) | 1989-10-18 | — | — | EP | disclosed |
| EP-0051467-B1 | HEXITOL DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) | 1986-08-13 | — | — | EP | disclosed |
| EP-0184162-A2 | Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-06-11 | — | — | EP | disclosed |
| US-4419522-A | ANTITUMOR AGENTS | CHINOIN GYOGYSZER VEGYESZETI TERMEKEK GYARA RT. (HU) | 1983-12-06 | — | — | US | disclosed |
| EP-0051467-A1 | Hexitol derivatives, their preparation and pharmaceutical compositions containing them | CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) | 1982-05-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230102146-A1 | MULTI-TARGET TYROSINE KINASE INHIBITOR | LCK, ABL1, DSTYK | TSHR 1922/4885LMNA 4857/4885NFKB1 1779/4885 |
| US-20230103337-A1 | MEDICINE FOR IMPROVING STATE OF PREGNANCY, AND USE THEREOF | PGF, SLC10A1, SLC26A4 | TSHR 1982/4885LMNA 2424/4885NFKB1 1572/4885 |
| US-11541040-B2 | Medicine for improving state of pregnancy, and use thereof | PGF, SLC10A1, SLC26A4 | TSHR 2169/4885LMNA 2875/4885NFKB1 1846/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.