SCHEMBL374773

SCHEMBL374773

O=[C]CCCCCCCCCCCCCCCCC(=O)O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.63
LMNA P02545 2/20 0.63
NFKB1 P19838 1/20 0.63
PMP22 Q01453 1/20 0.63
HSD17B10 Q99714 2/20 0.62
CYP1A2 P05177 1/20 0.62
CYP2D6 P10635 1/20 0.62
MAPT P10636 1/20 0.62
CYP2C9 P11712 1/20 0.62
CYP2C19 P33261 1/20 0.62
PTPN7 P35236 3/20 0.56
HMGCR P04035 3/20 0.56
GPR84 Q9NQS5 4/20 0.52
FFAR1 O14842 2/20 0.52
FFAR4 Q5NUL3 2/20 0.52
PPARG P37231 5/20 0.50
PPARD Q03181 5/20 0.50
PPARA Q07869 5/20 0.50
HDAC11 Q96DB2 4/20 0.50
ALDH1A1 P00352 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16701316 1.00 TSHR (0.63) TSHRLMNANFKB1PMP22HSD17B10
SCHEMBL970516 1.00 TSHR (0.63) TSHRLMNANFKB1PMP22HSD17B10
SCHEMBL7382880 1.00 TSHR (0.63) TSHRLMNANFKB1PMP22HSD17B10
SCHEMBL6539108 1.00 TSHR (0.63) TSHRLMNANFKB1PMP22HSD17B10
SCHEMBL3972155 1.00 TSHR (0.63) TSHRLMNANFKB1PMP22HSD17B10
SCHEMBL3980051 1.00 TSHR (0.63) TSHRLMNANFKB1PMP22HSD17B10
SCHEMBL1702085 1.00 TSHR (0.63) TSHRLMNANFKB1PMP22HSD17B10
SCHEMBL1654498 1.00 TSHR (0.63) TSHRLMNANFKB1PMP22HSD17B10
SCHEMBL1401237 1.00 TSHR (0.63) TSHRLMNANFKB1PMP22HSD17B10
SCHEMBL7292218 1.00 TSHR (0.63) TSHRLMNANFKB1PMP22HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 781 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024149820-A1 NMU RECEPTOR 2 AGONISTS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2024-07-18 WO claimed
WO-2024133382-A1 GLP1/GIP/NPY2 RECEPTOR TRIPLE AGONISTS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2024-06-27 WO claimed
CN-118079021-A Treatment or amelioration of metabolic disorders using GLP-1 receptor agonists coupled to Gastric Inhibitory Peptide Receptor (GIPR) antagonists 美国安进公司 2024-05-28 CN claimed
US-11965039-B2 Compstatin analogues and their medical uses ZP SPV 3 K/S (DK) 2024-04-23 US claimed
EP-4351630-A1 TREATMENT OF OBESITY AND OBESITY-RELATED DISORDERS Antag Therapeutics ApS (DK) 2024-04-17 EP claimed
EP-3551651-B1 ACYLATED GLP-1/GLP-2 DUAL AGONISTS ZEALAND PHARMA AS (DK) 2024-03-06 EP claimed
CN-117384274-A Acylated GLP-1/GLP-2 dual agonists 西兰制药公司 2024-01-12 CN claimed
US-20230405087-A9 ACYLATED GLP-1/GLP-2 DUAL AGONISTS ZEALAND PHARMA A/S (DK) 2023-12-21 US claimed
EP-4272751-A2 COMPSTATIN ANALOGUES AND THEIR MEDICAL USES ZP SPV 3 K/S (DK) 2023-11-08 EP claimed
US-20230340039-A1 NPY2 RECEPTOR AGONISTS BOEHRINGER INGELHEIM INT (DE) 2023-10-26 US claimed
WO-2002076495-A1 INSULIN PREPARATIONS, WHICH DO NOT CONTAIN ANY ZINC OR ONLY A SMALL QUANTITY OF ZINC AND WHICH HAVE AN IMPROVED STABILITY AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2002-10-03 WO claimed
EP-1121145-A1 INSULIN PREPARATIONS FOR PULMONARY DELIVERY CONTAINING MENTHOL Novo Nordisk A/S (DK) 2001-08-08 EP claimed
EP-1121144-A1 STABLE CONCENTRATED INSULIN PREPARATIONS FOR PULMONARY DELIVERY Novo Nordisk A/S (DK) 2001-08-08 EP claimed
US-6268343-B1 HUMAN GLUCAGON-LIKE PEPTIDE-1; MORE PROTRACTED PROFILE OF ACTION THAN THE PARENT PEPTIDES; TREATING DIABETES AND OBESITY; Liraglutide NOVO NORDISK A/S (DK) 2001-07-31 US claimed
US-6174856-B1 AQUEOUS PARENTERAL INSULIN MIXTURE STABILIZED WITH A GLYCYLGLYCINE BUFFER AND CALCIUM OR MAGNESIUM IONS NOVO NORDISK A/S (DK) 2001-01-16 US claimed
EP-1044016-A1 STABILISED INSULIN COMPOSITIONS NOVO NORDISK A/S (DK) 2000-10-18 EP claimed
WO-2000023098-A1 STABLE CONCENTRATED INSULIN PREPARATIONS FOR PULMONARY DELIVERY NOVO NORDISK A/S (DK) 2000-04-27 WO claimed
WO-2000023099-A1 INSULIN PREPARATIONS FOR PULMONARY DELIVERY CONTAINING MENTHOL NOVO NORDISK A/S (DK) 2000-04-27 WO claimed
WO-1999034821-A1 STABILISED INSULIN COMPOSITIONS NOVO NORDISK A/S (DK) 1999-07-15 WO claimed
US-4097665-A Diacylnucleosides and process for preparing the same ASAHI KASEI KOGYO KABUSHIKI KAISHA (JA) 1978-06-27 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11965039-B2 Compstatin analogues and their medical uses C1QBP, C9, VIP TSHR 1041/4885LMNA 1380/4885NFKB1 2017/4885
US-20230405087-A9 ACYLATED GLP-1/GLP-2 DUAL AGONISTS GLP1R, GIPR, GPR119 TSHR 313/4885LMNA 2721/4885NFKB1 4088/4885
US-20230340039-A1 NPY2 RECEPTOR AGONISTS NPY2R, NPY1R, NPY5R TSHR 259/4885LMNA 2884/4885NFKB1 3375/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.