SCHEMBL14012385

SCHEMBL14012385

C=c1c2ccccc2nc2cc3c(cc12)=Nc1ccccc1C3=O

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 3/20 0.34
ALDH1A1 P00352 3/20 0.34
SRC P12931 2/20 0.34
CTRB1 P17538 2/20 0.34
CCNE1 P24864 2/20 0.34
CDK2 P24941 2/20 0.34
RECQL P46063 1/20 0.34
HSD17B10 Q99714 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
RAB9A P51151 4/20 0.33
NPC1 O15118 3/20 0.33
KMT2A Q03164 7/20 0.33
MAPT P10636 6/20 0.33
MEN1 O00255 4/20 0.33
IDO1 P14902 3/20 0.33
TDO2 P48775 2/20 0.33
IDO2 Q6ZQW0 2/20 0.33
LMNA P02545 2/20 0.33
C1R P00736 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6731218 0.74 MEN1 (0.46) AHRALDH1A1SRCCTRB1CCNE1
Anthraquinone SCHEMBL5550279 0.61 MAPT (0.67) AHRALDH1A1RECQLTDP1RAB9A
SCHEMBL550601 0.59 IDO1 (0.39) AHRALDH1A1SRCCTRB1CCNE1
Anthraquinone SCHEMBL8972708 0.59 NPC1 (0.71) AHRALDH1A1RECQLHSD17B10TDP1
SCHEMBL28604179 0.59 MEN1 (0.46) AHRALDH1A1SRCCTRB1CCNE1
SCHEMBL10708525 0.58 RAB9A (0.54) AHRALDH1A1RECQLHSD17B10TDP1
SCHEMBL28426927 0.58 CDK2 (0.53) AHRALDH1A1SRCCTRB1CCNE1
SCHEMBL21316073 0.58 MEN1 (0.63) AHRALDH1A1SRCCTRB1CCNE1
SCHEMBL10689272 0.57 IDO1 (0.34) ALDH1A1RECQLTDP1KMT2AMAPT
SCHEMBL1750489 0.57 MEN1 (0.58) ALDH1A1RECQLTDP1RAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1620326-B1 EXTRUDED POLYPROPYLENE SHEETS CONTAINING BETA SPHERULITES MAYZO INC (US) 2008-12-10 EP disclosed