Anthraquinone

Anthraquinone

SCHEMBL8972708

O=C1c2ccccc2C(=O)c2ccccc21.c1ccc2nc3ccccc3cc2c1

nearest known ligand 0.71

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 7/20 0.71
RAB9A P51151 7/20 0.71
MAPT P10636 7/20 0.68
ALDH1A1 P00352 5/20 0.68
GLA P06280 2/20 0.68
HPGD P15428 2/20 0.68
ACHE P22303 1/20 0.68
KMT2A Q03164 6/20 0.55
MEN1 O00255 5/20 0.55
CDC25B P30305 1/20 0.55
SMN1; SMN2 Q16637 5/20 0.52
AHR P35869 1/20 0.52
HTR3A P46098 1/20 0.50
APEX1 P27695 1/20 0.49
CYP3A4 P08684 4/20 0.48
PABPC1 P11940 1/20 0.48
DNMT1 P26358 1/20 0.48
CASP1 P29466 1/20 0.48
CASP7 P55210 1/20 0.48
BCL2 P10415 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzanthrone SCHEMBL27947469 0.87 PABPC1 (0.72) NPC1RAB9AMAPTALDH1A1GLA
Anthraquinone SCHEMBL5550279 0.85 MAPT (0.67) NPC1RAB9AMAPTALDH1A1KMT2A
SCHEMBL31538695 0.84 RAB9A (1.00) NPC1RAB9AMAPTALDH1A1GLA
SCHEMBL7464992 0.84 RAB9A (1.00) NPC1RAB9AMAPTALDH1A1GLA
SCHEMBL7648567 0.84 RAB9A (0.86) NPC1RAB9AMAPTALDH1A1GLA
Anthraquinone SCHEMBL4973222 0.83 MEN1 (0.71) NPC1RAB9AMAPTALDH1A1KMT2A
Acridine SCHEMBL1772714 0.83 ALDH1A1 (1.00) NPC1RAB9AMAPTALDH1A1GLA
Acridine SCHEMBL29352289 0.83 ALDH1A1 (1.00) NPC1RAB9AMAPTALDH1A1GLA
Acridine SCHEMBL8339 0.83 ALDH1A1 (1.00) NPC1RAB9AMAPTALDH1A1GLA
Acridine SCHEMBL3045498 0.83 ALDH1A1 (1.00) NPC1RAB9AMAPTALDH1A1GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0649833-B1 Process for the preparation of anthraquinonamine compounds BASF AG (DE) 1996-02-28 EP claimed
CN-101379632-B Large area organic electronic devices and methods of fabricating the same GEN ELECTRIC 2011-08-10 CN disclosed
CN-101379632-A Large area organic electronic devices and methods of fabricating the same GEN ELECTRIC (US) 2009-03-04 CN disclosed