Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.52 |
| ▸ | RELA | Q04206 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | RAD52 | P43351 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MGAM | O43451 | 1/20 | 0.47 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SI | P14410 | 1/20 | 0.47 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7124063 | 0.79 | SMN1; SMN2 (0.68) | SMN1; SMN2MAPTNPC1RAB9ATDP1 | |
| SCHEMBL14013431 | 0.75 | MEN1 (0.46) | SMN1; SMN2MAPTTDP1KDM4ELMNA | |
| Bromide SCHEMBL11731030 | 0.74 | MAPT (0.56) | SMN1; SMN2MAPTNPC1RAB9ATDP1 | |
| SCHEMBL312393 | 0.73 | CES2 (0.68) | SMN1; SMN2MAPTLMNAKMT2AMEN1 | |
| SCHEMBL30512072 | 0.73 | CES2 (0.68) | SMN1; SMN2MAPTLMNAKMT2AMEN1 | |
| SCHEMBL3006822 | 0.72 | KMT2A (0.52) | SMN1; SMN2MAPTNPC1RAB9ATDP1 | |
| SCHEMBL28133147 | 0.72 | CES2 (0.66) | SMN1; SMN2MAPTLMNAKMT2AMEN1 | |
| SCHEMBL1986403 | 0.71 | CES2 (0.70) | SMN1; SMN2MAPTLMNAKMT2AMEN1 | |
| SCHEMBL18302433 | 0.69 | TP53 (0.65) | SMN1; SMN2MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL18302432 | 0.69 | TP53 (0.65) | SMN1; SMN2MAPTKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080287511-A1 | Anthelmintic Imidazol-Thiazole Derivates | AVISTAR COMMUNICATIONS CORPORATION | 2008-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080287511-A1 | Anthelmintic Imidazol-Thiazole Derivates | NOD1, IL33, IL5 | SMN1; SMN2 3614/4885MAPT 2760/4885NPC1 4006/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.