Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | PYGL | P06737 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4710027 | 1.00 | ADORA3 (0.41) | ADORA3ADORA2AADORA1ALDH1A1MAPT | |
| SCHEMBL4707958 | 0.92 | KDM4E (0.38) | ADORA3ADORA2AADORA1ALDH1A1MAPT | |
| SCHEMBL14014038 | 0.92 | KDM4E (0.38) | ADORA3ADORA2AADORA1ALDH1A1MAPT | |
| SCHEMBL14015113 | 0.87 | KMT2A (0.42) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL4710029 | 0.86 | ADORA3 (0.43) | ADORA3ADORA2AADORA1ALDH1A1MAPT | |
| SCHEMBL14015104 | 0.81 | ADAMTS4 (0.39) | MAPTMEN1KMT2AKDM4ERAB9A | |
| SCHEMBL4709065 | 0.80 | PLAT (0.44) | ADORA3ADORA2AADORA1ALDH1A1MAPT | |
| SCHEMBL14015115 | 0.80 | ALDH1A1 (0.38) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL14015105 | 0.79 | ADAMTS4 (0.38) | MAPTMEN1KMT2AKDM4ERAB9A | |
| SCHEMBL4707957 | 0.79 | KDM4E (0.43) | ADORA3ADORA2AADORA1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7449488-B2 | Pyrazolopyrimidines as protein kinase inhibitors | SCHERING CORPORATION (US) | 2008-11-11 | — | — | US | disclosed |
| US-7449488-B2 | Pyrazolopyrimidines as protein kinase inhibitors | SCHERING CORPORATION (US) | 2008-11-11 | — | — | US | disclosed |
| US-7196111-B2 | Pyrazolo[1,5a]pyrimidine compounds as antiviral agents | SCHERING CORPORATION (US) | 2007-03-27 | — | — | US | disclosed |
| US-7196111-B2 | Pyrazolo[1,5a]pyrimidine compounds as antiviral agents | SCHERING CORPORATION (US) | 2007-03-27 | — | — | US | disclosed |