Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 6/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL721176 | 1.00 | MEN1 (0.50) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL260944 | 0.95 | — | — | |
| SCHEMBL30737022 | 0.91 | TSHR (0.46) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL7648165 | 0.91 | TSHR (0.48) | MEN1KMT2ATSHRHSD17B10MGAM | |
| SCHEMBL6463788 | 0.88 | TSHR (0.50) | MEN1KMT2ATSHRHTTMAPT | |
| SCHEMBL28681666 | 0.84 | MEN1 (0.52) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL5049754 | 0.84 | TSHR (0.42) | MEN1KMT2ATSHRALDH1A1HSD17B10 | |
| SCHEMBL31672720 | 0.84 | TSHR (0.42) | MEN1KMT2ATSHRALDH1A1HSD17B10 | |
| SCHEMBL15360069 | 0.84 | TSHR (0.42) | MEN1KMT2ATSHRALDH1A1HSD17B10 | |
| SCHEMBL16917910 | 0.84 | TSHR (0.42) | MEN1KMT2ATSHRALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024232597-A1 | 4-CHROMANONE COMPOUNDS THAT DEGRADE WDR5 AND USES THEREOF | 엘젠테라퓨틱스 주식회사 | 2024-11-14 | — | — | WO | disclosed |
| US-12083108-B2 | Compounds for targeting mutant huntingtin protein and uses thereof | CHDI FOUNDATION, INC. (US) | 2024-09-10 | — | — | US | disclosed |
| WO-2023090829-A1 | LOW-MOLECULAR-WEIGHT COMPOUND FOR REGULATING MLL1-WDR5 INTERACTION AND USE THEREOF | 엘젠테라퓨틱스 주식회사 | 2023-05-25 | — | — | WO | disclosed |
| US-20220409600-A1 | COMPOUNDS FOR TARGETING MUTANT HUNTINGTIN PROTEIN AND USES THEREOF | CHDI FOUNDATION, INC. | 2022-12-29 | — | — | US | disclosed |
| US-11389438-B2 | Compounds for targeting mutant huntingtin protein and uses thereof | CHDI FOUNDATION, INC. (US) | 2022-07-19 | — | — | US | disclosed |
| EP-3931186-A1 | COMPOUNDS FOR TARGETING MUTANT HUNTINGTIN PROTEIN AND USES THEREOF | CHDI Foundation, Inc. (US) | 2022-01-05 | — | — | EP | disclosed |
| US-20200276176-A1 | COMPOUNDS FOR TARGETING MUTANT HUNTINGTIN PROTEIN AND USES THEREOF | CHDI FOUNDATION, INC. | 2020-09-03 | — | — | US | disclosed |
| EP-2292707-B1 | INK COMPOSITION FOR FORMING AN INSULATING FILM AND AN INSULATING FILM FORMED FROM SAID INK COMPOSITION | DAINIPPON INK & CHEMICALS (JP) | 2017-03-08 | — | — | EP | disclosed |
| CN-103492496-B | Blend composition, flexible pipe material and method for manufacturing blend | SAINT-GOBAIN PERFORMANCE PLASTICS CORP. (US) | 2016-11-30 | — | — | CN | disclosed |
| US-8791173-B2 | Ink composition for forming insulating film and insulating film formed from the ink composition | DIC CORPORATION (JP) | 2014-07-29 | — | — | US | disclosed |
| CN-103460138-A | Polymer-containing developer | NISSAN CHEMICAL IND LTD | 2013-12-18 | — | — | CN | disclosed |
| CN-101517487-B | Radiation-sensitive composition, method for forming silica-based coating film, device and member having silica-based coating film, and photosensitizer for insulating film | HITACHI CHEMICAL CO LTD | 2012-08-08 | — | — | CN | disclosed |
| US-8206901-B2 | Method for the synthesis of a bifunctional complex | NUEVOLUTION A/S (DK) | 2012-06-26 | — | — | US | disclosed |
| US-20110086946-A1 | INK COMPOSITION FOR FORMING INSULATING FILM AND INSULATING FILM FORMED FROM THE INK COMPOSITION | DIC CORPORATION (JP) | 2011-04-14 | — | — | US | disclosed |
| EP-2292707-A1 | INK COMPOSITION FOR FORMING AN INSULATING FILM AND AN INSULATING FILM FORMED FROM SAID INK COMPOSITION | DIC Corporation (JP) | 2011-03-09 | — | — | EP | disclosed |
| CN-101517487-A | Radiation-sensitive composition, method for forming silica-based coating film, device and member having silica-based coating film, and photosensitizer for insulating film | HITACHI CHEMICAL CO LTD (JP) | 2009-08-26 | — | — | CN | disclosed |
| US-4267260-A | Developer for lithographic printing plate | MITSUBISHI CHEMICAL INDUSTRIES, LTD. (JP) | 1981-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12083108-B2 | Compounds for targeting mutant huntingtin protein and uses thereof | HTT, HYPK, UBQLN2 | MEN1 3543/4885KMT2A 933/4885TSHR 3537/4885 |
| US-11389438-B2 | Compounds for targeting mutant huntingtin protein and uses thereof | HTT, HYPK, UBQLN2 | MEN1 3543/4885KMT2A 933/4885TSHR 3537/4885 |
| US-20200276176-A1 | COMPOUNDS FOR TARGETING MUTANT HUNTINGTIN PROTEIN AND USES THEREOF | HTT, HYPK, UBQLN2 | MEN1 3543/4885KMT2A 933/4885TSHR 3537/4885 |
| US-20220409600-A1 | COMPOUNDS FOR TARGETING MUTANT HUNTINGTIN PROTEIN AND USES THEREOF | HTT, HYPK, UBQLN2 | MEN1 3543/4885KMT2A 933/4885TSHR 3537/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.