Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1203240 | 0.85 | ALOX15 (0.50) | ALOX15ALDH1A1CYP1A2CA12CA1 | |
| SCHEMBL1706932 | 0.85 | HDAC6 (0.38) | NFKB1NFKB2RELAHDAC6HDAC1 | |
| SCHEMBL8806268 | 0.79 | HDAC6 (0.41) | NFKB1NFKB2RELAHDAC6HDAC1 | |
| SCHEMBL3884537 | 0.79 | HDAC6 (0.44) | NFKB1NFKB2RELAHDAC6HDAC1 | |
| SCHEMBL24737134 | 0.78 | NFKB1 (0.45) | NFKB1NFKB2RELAHDAC6HDAC1 | |
| SCHEMBL10568938 | 0.78 | ALOX15 (0.39) | NFKB1NFKB2RELAALOX15ALDH1A1 | |
| SCHEMBL14336042 | 0.77 | DGAT1 (0.41) | NFKB1NFKB2RELAHDAC6HDAC1 | |
| SCHEMBL11522989 | 0.76 | ALOX15 (0.46) | ALOX15ALDH1A1CYP1A2CA12CA1 | |
| SCHEMBL10558566 | 0.76 | NFKB1 (0.44) | NFKB1NFKB2RELAHDAC6HDAC1 | |
| SCHEMBL5580137 | 0.76 | AKT1 (0.39) | NFKB1NFKB2RELAHDAC6HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2723723-B1 | N-OXY PYRAZOLO-TRIAZEPINE-DIONE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2017-02-01 | — | — | EP | disclosed |
| US-9282743-B2 | Chemical compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2016-03-15 | — | — | US | disclosed |
| US-20140148339-A1 | CHEMICAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140148339-A1 | CHEMICAL COMPOUNDS | DDT, CYP1B1, CYP1A1 | NFKB1 3899/4885NFKB2 4330/4885RELA 4633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.