Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CTH | P32929 | 1/20 | 0.33 |
| ▸ | CBS | P35520 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8806268 | 0.82 | HDAC6 (0.41) | HDAC6HDAC1HDAC2NFKB1NFKB2 | |
| SCHEMBL3884537 | 0.82 | HDAC6 (0.44) | HDAC6HDAC1HDAC2NFKB1NFKB2 | |
| SCHEMBL1706932 | 0.79 | HDAC6 (0.38) | HDAC6HDAC1HDAC2NFKB1NFKB2 | |
| SCHEMBL1401436 | 0.78 | AKT1 (0.39) | HDAC6HDAC1HDAC2NFKB1NFKB2 | |
| SCHEMBL5580137 | 0.78 | AKT1 (0.39) | HDAC6HDAC1HDAC2NFKB1NFKB2 | |
| SCHEMBL5555258 | 0.77 | HDAC6 (0.57) | HDAC6HDAC1HDAC2NFKB1NFKB2 | |
| SCHEMBL3884535 | 0.76 | HDAC6 (0.40) | HDAC6HDAC1HDAC2NFKB1NFKB2 | |
| SCHEMBL959919 | 0.75 | HDAC6 (0.34) | HDAC6HDAC1HDAC2CA14 | |
| SCHEMBL15734005 | 0.74 | NFKB1 (0.44) | HDAC6HDAC1HDAC2NFKB1NFKB2 | |
| SCHEMBL4676227 | 0.74 | HDAC6 (0.46) | HDAC6HDAC1HDAC2TSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3456749-B1 | A SUBSTITUTED POLYVINYL ALCOHOL REAGENT | PVAC MEDICAL TECH LTD (CY) | 2021-07-14 | — | — | EP | disclosed |
| EP-3456749-A1 | A SUBSTITUTED POLYVINYAL ALCOHOL REAGENT | PVAC Medical Technologies Ltd. (CY) | 2019-03-20 | — | — | EP | disclosed |
| EP-2254944-B1 | COMPOSITION FOR THE FORMATION OF GELS | PVAC MEDICAL TECH LTD (CY) | 2018-12-19 | — | — | EP | disclosed |
| US-9585987-B2 | Composition for the formation of gels | PVAC MEDICAL TECHNOLOGIES LTD (CY) | 2017-03-07 | — | — | US | disclosed |
| US-20110008444-A1 | COMPOSITION FOR THE FORMATION OF GELS | IPR-SYSTEMS SWEDEN AB (SE) | 2011-01-13 | — | — | US | disclosed |