Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 10/20 | 0.32 |
| ▸ | CTSK | P43235 | 3/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | PTPRB | P23467 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14014469 | 0.85 | CA2 (0.32) | DGAT1CA1CA2CA7AAK1 | |
| SCHEMBL14014467 | 0.85 | MAPT (0.39) | DGAT1CA1CA2CA7AAK1 | |
| SCHEMBL14014476 | 0.83 | — | — | |
| SCHEMBL88463 | 0.81 | DGAT1 (0.45) | DGAT1CA1CA2CA7CTSK | |
| SCHEMBL13201421 | 0.73 | DGAT1 (0.38) | DGAT1CA1CA2CA7CTSK | |
| SCHEMBL13201422 | 0.71 | MAPT (0.43) | DGAT1CA1CA2CA7CTSK | |
| SCHEMBL15113634 | 0.71 | CA1 (0.41) | CA1CA2CA7CTSKCA12 | |
| SCHEMBL1691164 | 0.71 | DGAT1 (0.33) | DGAT1 | |
| SCHEMBL15116461 | 0.69 | CA1 (0.39) | DGAT1CA1CA2CA7CTSK | |
| SCHEMBL88462 | 0.69 | CTSK (0.41) | CA1CA2CA7CTSKCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7449493-B2 | Diamines as modulators of chemokine receptor activity | BRISTOL-MYERS SQUIBB PHARMACEUTICAL COMPANY (US) | 2008-11-11 | — | — | US | disclosed |