SCHEMBL14015181

SCHEMBL14015181

CCCCN1C(=O)C(=Cc2ccc(N(CC)CC)cc2)C(=O)N(CCCC)C1=S

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 14/20 0.54
MEN1 O00255 13/20 0.54
KMT2A Q03164 13/20 0.54
MAPT P10636 10/20 0.54
NPSR1 Q6W5P4 4/20 0.54
LMNA P02545 3/20 0.54
TDP1 Q9NUW8 2/20 0.54
KDM4E B2RXH2 2/20 0.54
MAPK1 P28482 2/20 0.54
GAA P10253 1/20 0.54
NTSR1 P30989 1/20 0.54
HPGD P15428 8/20 0.51
CYP1A2 P05177 3/20 0.51
CYP2C19 P33261 3/20 0.51
CRHBP P24387 2/20 0.51
CRHR2 Q13324 2/20 0.51
CYP3A4 P08684 1/20 0.51
L3MBTL1 Q9Y468 5/20 0.51
RECQL P46063 4/20 0.51
THRB P10828 4/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14038834 0.92 ALDH1A1 (0.49) ALDH1A1MEN1KMT2AMAPTNPSR1
SCHEMBL125192 0.88 KMT2A (0.64) ALDH1A1MEN1KMT2AMAPTNPSR1
SCHEMBL13410799 0.77 ALDH1A1 (0.58) ALDH1A1MEN1KMT2AMAPTNPSR1
SCHEMBL14181829 0.74 NOX4 (0.74) ALDH1A1MEN1KMT2AMAPTNPSR1
SCHEMBL14174577 0.72 ALDH1A1 (0.56) ALDH1A1MEN1KMT2AMAPTNPSR1
SCHEMBL11153567 0.71 MAPT (0.43) ALDH1A1MEN1KMT2AMAPTLMNA
SCHEMBL10134151 0.71 TNFRSF1A (0.49) ALDH1A1MEN1KMT2AMAPTNPSR1
SCHEMBL14680296 0.71 KMT2A (0.64) ALDH1A1MEN1KMT2AMAPTNPSR1
SCHEMBL9432000 0.71 SMN1; SMN2 (0.61) ALDH1A1MEN1KMT2AMAPTTDP1
SCHEMBL29323764 0.71 MEN1 (1.00) ALDH1A1MEN1KMT2AMAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7435529-B2 Photosensitive composition and image recording method using the same FUJIFILM CORPORATION (JP) 2008-10-14 US disclosed