Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.35 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 3/20 | 0.33 |
| ▸ | CA6 | P23280 | 3/20 | 0.33 |
| ▸ | CA7 | P43166 | 3/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13813061 | 0.95 | CYP2C9 (0.34) | CYP2C19CYP2C9KDM4AHIF1ATET2 | |
| SCHEMBL16330324 | 0.90 | DNM1 (0.33) | KDM4AHIF1ATET2DOHHCA12 | |
| SCHEMBL10100177 | 0.88 | CA12 (0.43) | CYP2C19CYP2C9CA12CA6CA7 | |
| SCHEMBL14134895 | 0.87 | DNM1 (0.31) | KDM4AHIF1ATET2DOHHDNM1 | |
| SCHEMBL15963174 | 0.86 | CA12 (0.48) | CA12CA6CA7CA9CA14 | |
| SCHEMBL12219612 | 0.84 | KDM4A (0.38) | CYP2C19CYP2C9KDM4AHIF1ATET2 | |
| SCHEMBL13756030 | 0.83 | FAAH (0.40) | CYP2C19CYP2C9KDM4AHIF1ATET2 | |
| SCHEMBL14015341 | 0.83 | DNM1 (0.35) | CYP2C19KDM4AHIF1ATET2DOHH | |
| SCHEMBL8239576 | 0.82 | DNM1 (0.37) | CYP2C19CYP2C9KDM4AHIF1ATET2 | |
| SCHEMBL13374199 | 0.82 | KDM4A (0.36) | CYP2C19CYP2C9KDM4AHIF1ATET2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080267903-A1 | Cationic polyamines and dendrimeric polymers; anti-proliferative agents; for treatment of neoplasms and tumours, inflammatory disorders, autoimmune disorders, psoriasis, and atherosclerosis; gene therapy | UNIVERSITY COLLEGE LONDON (GB) | 2008-10-30 | — | — | US | disclosed |
| US-20080267903-A1 | Cationic polyamines and dendrimeric polymers; anti-proliferative agents; for treatment of neoplasms and tumours, inflammatory disorders, autoimmune disorders, psoriasis, and atherosclerosis; gene therapy | UNIVERSITY COLLEGE LONDON (GB) | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080267903-A1 | Cationic polyamines and dendrimeric polymers; anti-proliferative agents; for treatment of neoplasms and tumours, inflammatory disorders, autoimmune disorders, psoriasis, and atherosclerosis; gene therapy | PCNA, SSB, PKD1 | CYP2C19 4841/4885CYP2C9 4866/4885KDM4A 2860/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.