Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIMP3 | P35625 | 6/20 | 0.67 |
| ▸ | RECQL | P46063 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | PKM | P14618 | 5/20 | 0.50 |
| ▸ | P2RX1 | P51575 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.50 |
| ▸ | APEX1 | P27695 | 4/20 | 0.50 |
| ▸ | BLM | P54132 | 4/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | BRCA1 | P38398 | 3/20 | 0.50 |
| ▸ | STAT1 | P42224 | 3/20 | 0.50 |
| ▸ | STAT5A | P42229 | 3/20 | 0.50 |
| ▸ | STAT5B | P51692 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14506109 | 1.00 | TIMP3 (0.67) | TIMP3RECQLKMT2AHSD17B10TDP1 | |
| SCHEMBL1902159 | 0.82 | TIMP3 (1.00) | TIMP3RECQLKMT2AHSD17B10TDP1 | |
| SCHEMBL12410284 | 0.76 | TIMP3 (0.86) | TIMP3RECQLKMT2AHSD17B10TDP1 | |
| SCHEMBL21645072 | 0.75 | RECQL (0.86) | TIMP3RECQLKMT2AHSD17B10TDP1 | |
| SCHEMBL14506111 | 0.74 | TIMP3 (0.67) | TIMP3RECQLKMT2AHSD17B10TDP1 | |
| SCHEMBL14081252 | 0.71 | TIMP3 (0.47) | TIMP3RECQLKMT2AHSD17B10TDP1 | |
| SCHEMBL14506107 | 0.71 | RECQL (0.74) | TIMP3RECQLKMT2AHSD17B10TDP1 | |
| SCHEMBL12903191 | 0.71 | TIMP3 (0.72) | TIMP3RECQLKMT2AHSD17B10TDP1 | |
| SCHEMBL12410283 | 0.71 | TIMP3 (0.75) | TIMP3RECQLKMT2AHSD17B10TDP1 | |
| SCHEMBL16921052 | 0.71 | TIMP3 (0.75) | TIMP3RECQLKMT2AHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8367677-B2 | Comprising trihydroxy phenyl subunits; selectin inhibitors; side effect reduction; 3-{3-[3-(3,4,5-Trihydroxy-phenyl)-propionylamino]-phenylamino}-benzoic acid | REVOTAR BIOPHARMACEUTICALS AG (DE) | 2013-02-05 | — | — | US | disclosed |
| US-20080249107-A1 | Non-Glycosylated/Non-Glycosidic/Non-Peptidic Small Molecule Psgl-1 Mimetics for the Treatment of Inflammatory Disorders | REVOTAR BIOPHARMACEUTICALS AG (DE) | 2008-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249107-A1 | Non-Glycosylated/Non-Glycosidic/Non-Peptidic Small Molecule Psgl-1 Mimetics for the Treatment of Inflammatory Disorders | SELP, SELPLG, SELE | TIMP3 838/4885RECQL 4093/4885KMT2A 4414/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.