Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.42 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | CAD | P27708 | 1/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.37 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8894678 | 0.91 | SLC7A5 (0.52) | ALOX15SLC1A3SLC1A2SLC1A1SLC7A5 | |
| SCHEMBL839402 | 0.88 | SLC7A5 (0.54) | ALOX15ALDH1A1LMNAHSD17B10GAA | |
| SCHEMBL133092 | 0.88 | SLC7A5 (0.54) | ALOX15ALDH1A1LMNAHSD17B10GAA | |
| SCHEMBL196637 | 0.88 | SLC7A5 (0.54) | ALOX15ALDH1A1LMNAHSD17B10GAA | |
| SCHEMBL2953404 | 0.86 | ALOX15 (0.41) | ALOX15ALDH1A1LMNAHSD17B10GAA | |
| SCHEMBL8038311 | 0.86 | ALOX15 (0.41) | ALOX15ALDH1A1LMNAHSD17B10GAA | |
| Hydrochloric Acid SCHEMBL10887590 | 0.86 | SLC7A5 (0.52) | ALOX15ALDH1A1LMNAHSD17B10GAA | |
| Hydrochloric Acid SCHEMBL133091 | 0.86 | SLC7A5 (0.52) | ALOX15ALDH1A1LMNAHSD17B10GAA | |
| SCHEMBL10686184 | 0.86 | ALOX15 (0.41) | ALOX15ALDH1A1LMNAHSD17B10GAA | |
| SCHEMBL7554622 | 0.86 | CYP2C19 (0.45) | ALOX15ALDH1A1LMNAHSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7435831-B2 | Bicyclic and bridged nitrogen heterocycles | CHEMOCENTRYX, INC. (US) | 2008-10-14 | — | — | US | disclosed |
| US-7435830-B2 | Bicyclic and bridged nitrogen heterocycles | CHEMOCENTRYX, INC. (US) | 2008-10-14 | — | — | US | disclosed |