Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 4/20 | 0.35 |
| ▸ | METAP1 | P53582 | 3/20 | 0.35 |
| ▸ | CAD | P27708 | 1/20 | 0.34 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7557066 | 1.00 | CYP2C19 (0.45) | CYP2C19CYP3A4GAAALOX15ALDH1A1 | |
| SCHEMBL1301349 | 0.88 | ENPEP (0.47) | ALOX15SLC7A5SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL14016339 | 0.86 | ALOX15 (0.48) | CYP2C19GAAALOX15ALDH1A1LMNA | |
| SCHEMBL19387915 | 0.84 | CYP2C19 (0.46) | CYP2C19CYP3A4GAAALOX15ALDH1A1 | |
| SCHEMBL196637 | 0.84 | SLC7A5 (0.54) | CYP2C19GAAALOX15ALDH1A1LMNA | |
| SCHEMBL12975795 | 0.84 | CYP2C19 (0.46) | CYP2C19CYP3A4GAAALOX15ALDH1A1 | |
| SCHEMBL133092 | 0.84 | SLC7A5 (0.54) | CYP2C19GAAALOX15ALDH1A1LMNA | |
| SCHEMBL839402 | 0.84 | SLC7A5 (0.54) | CYP2C19GAAALOX15ALDH1A1LMNA | |
| SCHEMBL18410487 | 0.84 | CYP3A4 (0.56) | CYP2C19CYP3A4GAAALOX15ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10887590 | 0.83 | SLC7A5 (0.52) | CYP2C19GAAALOX15ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020115721-A1 | Esters of alkycarboxy amino acids as prodrugs of modulators of the kainate receptor | ANNOVIS, INC. | 2002-08-22 | — | — | US | claimed |
| WO-2002055479-A2 | ESTERS OF ALKYLCARBOXY AMINO ACIDS AS PRODRUGS OF MODULATORS OF THE KAINATE RECEPTOR | ANNOVIS, INC. (US) | 2002-07-18 | — | — | WO | claimed |
| US-20020115721-A1 | Esters of alkycarboxy amino acids as prodrugs of modulators of the kainate receptor | ANNOVIS, INC. | 2002-08-22 | — | — | US | disclosed |
| WO-2002055479-A2 | ESTERS OF ALKYLCARBOXY AMINO ACIDS AS PRODRUGS OF MODULATORS OF THE KAINATE RECEPTOR | ANNOVIS, INC. (US) | 2002-07-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020115721-A1 | Esters of alkycarboxy amino acids as prodrugs of modulators of the kainate receptor | GRIK1, GRIK2, GRIK4 | CYP2C19 1787/4885CYP3A4 2346/4885GAA 753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.