SCHEMBL839402

SCHEMBL839402

CCOC(=O)[C@H](N)CC(C)C

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.54
ALOX15 P16050 1/20 0.42
SLC1A3 P43003 1/20 0.42
SLC1A2 P43004 1/20 0.42
ALDH1A1 P00352 6/20 0.40
ANPEP P15144 5/20 0.40
RNPEP Q9H4A4 2/20 0.40
DNPEP Q9ULA0 1/20 0.40
LMNA P02545 1/20 0.39
HSD17B10 Q99714 1/20 0.39
METAP2 P50579 2/20 0.38
METAP1 P53582 2/20 0.38
PPID Q08752 1/20 0.38
GAA P10253 2/20 0.37
MGAM O43451 1/20 0.37
SI P14410 1/20 0.37
MGAM2 Q2M2H8 1/20 0.37
SOAT1 P35610 1/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C9 P11712 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL133092 1.00 SLC7A5 (0.54) SLC7A5ALOX15SLC1A3SLC1A2ALDH1A1
SCHEMBL196637 1.00 SLC7A5 (0.54) SLC7A5ALOX15SLC1A3SLC1A2ALDH1A1
Hydrochloric Acid SCHEMBL10887590 0.98 SLC7A5 (0.52) SLC7A5ALOX15SLC1A3SLC1A2ALDH1A1
Hydrochloric Acid SCHEMBL818970 0.98 SLC7A5 (0.52) SLC7A5ALOX15SLC1A3SLC1A2ALDH1A1
Hydrochloric Acid SCHEMBL133091 0.98 SLC7A5 (0.52) SLC7A5ALOX15SLC1A3SLC1A2ALDH1A1
Hydrochloric Acid SCHEMBL6846663 0.96 SLC7A5 (0.50) SLC7A5ALOX15SLC1A3SLC1A2ALDH1A1
SCHEMBL10866196 0.94 SLC7A5 (0.48) SLC7A5ALOX15SLC1A3SLC1A2ALDH1A1
Phosphoric Acid SCHEMBL28734810 0.92 SLC7A5 (0.47) SLC7A5ALOX15SLC1A3SLC1A2ANPEP
Sulfuric Acid SCHEMBL28734782 0.92 SLC7A5 (0.47) SLC7A5ALOX15SLC1A3SLC1A2ALDH1A1
SCHEMBL28856635 0.90 SLC7A5 (0.45) SLC7A5ALOX15SLC1A3SLC1A2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119667035-A Method for rapidly detecting chiral substances in white spirit and fermented grains and application 宜宾五粮液股份有限公司 2025-03-21 CN claimed
CN-119667035-A Method for rapidly detecting chiral substances in white spirit and fermented grains and application 宜宾五粮液股份有限公司 2025-03-21 CN disclosed
CN-117794580-A Polypeptide coupling medicine 肿瘤多肽有限公司 2024-03-29 CN disclosed
WO-2022263679-A1 PEPTIDE DRUG CONJUGATES ONCOPEPTIDES AB (SE) 2022-12-22 WO disclosed
EP-2852603-B1 D-AMINO ACID COMPOUNDS FOR LIVER DISEASE IDENIX PHARMACEUTICALS LLC (US) 2021-05-12 EP disclosed
US-20190292149-A1 ARYL SUBSTITUTED INDOLES AND THE USE THEREOF PURDUE PHARMA LP (US) 2019-09-26 US disclosed
US-10202344-B2 Aryl substituted indoles and the use thereof PURDUE PHARMA L.P. (US) 2019-02-12 US disclosed
EP-2906579-B1 2'-CHLORO NUCLEOSIDE ANALOGS FOR HCV INFECTION IDENIX PHARMACEUTICALS LLC (US) 2018-04-18 EP disclosed
US-20180022699-A1 ARYL SUBSTITUTED INDOLES AND THE USE THEREOF PURDUE PHARMA L.P. 2018-01-25 US disclosed
US-20180022699-A1 ARYL SUBSTITUTED INDOLES AND THE USE THEREOF PURDUE PHARMA L.P. 2018-01-25 US disclosed
EP-2889293-A1 THIAZINE AMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION AND USE THEREOF Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China (CN) 2015-07-01 EP disclosed
US-20130296281-A1 Aryl Substituted Indoles and Their Use as Blockers of Sodium Channels PURDUE PHARMA L.P. (US) 2013-11-07 US disclosed
CN-101248184-B Process for production of optically active (S or R)-a-amino acid or optically active (S or R)-a -amino acid ester UBE INDUSTRIES 2013-01-16 CN disclosed
US-8143052-B2 Process for preparing optically active (S or R)-α amino acid and (R or S)-α amino acid ester in one phase organic reaction medium UBE INDUSTRIES, LTD. (JP) 2012-03-27 US disclosed
CN-101248184-A Process for production of optically active (S or R)-a-amino acid or optically active (S or R)-a -amino acid ester UBE INDUSTRIES (JP) 2008-08-20 CN disclosed
US-20080153801-A1 Benzoxazepine compounds, their production and use TAKEDA PHARMACEUTICAL COMPANY LIMITED 2008-06-26 US disclosed
US-4616002-A HYPOTENSIVE AGENTS CIBA-GEIGY CORPORATION (US) 1986-10-07 US disclosed
US-4572894-A USING AMINOACYL-TRNA SYNTHETASE AS CONDENSING AGENT Imahori, Kazutomo (JP) 1986-02-25 US disclosed
EP-0086053-B1 PROCESS FOR SYNTHESIZING PEPTIDES OR PEPTIDE DERIVATIVES Imahori, Kazutomo (JP) 1986-01-02 EP disclosed
EP-0086053-A1 Process for synthesizing peptides or peptide derivatives Imahori, Kazutomo (JP) 1983-08-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130296281-A1 Aryl Substituted Indoles and Their Use as Blockers of Sodium Channels SCN5A, TRPV1, TRPV5 SLC7A5 301/4885ALOX15 925/4885SLC1A3 382/4885
US-20190292149-A1 ARYL SUBSTITUTED INDOLES AND THE USE THEREOF TRPC5, TRPV5, TRPV1 SLC7A5 242/4885ALOX15 607/4885SLC1A3 465/4885
US-20180022699-A1 ARYL SUBSTITUTED INDOLES AND THE USE THEREOF TRPC5, TRPV5, TRPV1 SLC7A5 242/4885ALOX15 607/4885SLC1A3 465/4885
US-10202344-B2 Aryl substituted indoles and the use thereof TRPC5, TRPV5, TRPV1 SLC7A5 242/4885ALOX15 607/4885SLC1A3 465/4885
US-20080153801-A1 Benzoxazepine compounds, their production and use CETP, PCSK9, LPL SLC7A5 2699/4885ALOX15 108/4885SLC1A3 3684/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.