Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | BRD1 | O95696 | 1/20 | 0.38 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14110195 | 0.86 | ESR1 (0.46) | ESR1KMT2AALDH1A1MEN1HPGD | |
| SCHEMBL14016785 | 0.85 | MEN1 (0.46) | ESR1KMT2AALDH1A1MEN1SCN2A | |
| SCHEMBL18470146 | 0.82 | MAPT (0.56) | ESR1KMT2AALDH1A1MEN1HPGD | |
| SCHEMBL14016790 | 0.82 | ALDH1A1 (0.51) | ESR1KMT2AALDH1A1MEN1HPGD | |
| SCHEMBL14044193 | 0.75 | ESR1 (0.48) | ESR1KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL18470153 | 0.75 | MAPT (0.50) | ESR1KMT2AALDH1A1MEN1HPGD | |
| SCHEMBL14016799 | 0.74 | ALDH1A1 (0.48) | ESR1KMT2AALDH1A1MEN1HPGD | |
| SCHEMBL11722412 | 0.73 | SCN2A (0.55) | ESR1KMT2AALDH1A1MEN1HPGD | |
| SCHEMBL2919813 | 0.72 | HSD17B10 (0.50) | ESR1KMT2AALDH1A1MEN1CASP1 | |
| SCHEMBL6392226 | 0.70 | SCN2A (0.66) | ESR1KMT2AALDH1A1MEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7432029-B2 | Electrophotographic photoreceptor containing asymmetrical naphthalenetetracarboxylic acid diimide derivatives and electrophotographic imaging apparatus employing the photoreceptor | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2008-10-07 | — | — | US | disclosed |