Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | BRD1 | O95696 | 1/20 | 0.42 |
| ▸ | TAF1 | P21675 | 1/20 | 0.42 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14016794 | 0.92 | ALDH1A1 (0.48) | ALDH1A1LMNAMAPK1SMN1; SMN2MEN1 | |
| SCHEMBL14016785 | 0.92 | MEN1 (0.46) | ALDH1A1LMNAMAPK1SMN1; SMN2MEN1 | |
| SCHEMBL14016781 | 0.92 | ALDH1A1 (0.48) | ALDH1A1LMNAMAPK1SMN1; SMN2MEN1 | |
| SCHEMBL6154621 | 0.90 | LMNA (0.51) | ALDH1A1LMNAMAPK1SMN1; SMN2MEN1 | |
| SCHEMBL14016764 | 0.74 | ESR1 (0.48) | ALDH1A1SMN1; SMN2MEN1KMT2AESR1 | |
| SCHEMBL12556877 | 0.73 | TDP1 (0.56) | ALDH1A1LMNAMAPK1SMN1; SMN2MEN1 | |
| SCHEMBL8089043 | 0.73 | ALDH1A1 (0.52) | ALDH1A1LMNAMAPK1SMN1; SMN2L3MBTL1 | |
| SCHEMBL517482 | 0.72 | ALDH1A1 (0.46) | ALDH1A1LMNASMN1; SMN2KMT2APOLB | |
| SCHEMBL6370714 | 0.71 | ALDH1A1 (0.50) | ALDH1A1LMNAMAPK1SMN1; SMN2L3MBTL1 | |
| SCHEMBL22028444 | 0.70 | SIRT6 (0.61) | ALDH1A1LMNASMN1; SMN2KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7432029-B2 | Electrophotographic photoreceptor containing asymmetrical naphthalenetetracarboxylic acid diimide derivatives and electrophotographic imaging apparatus employing the photoreceptor | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2008-10-07 | — | — | US | disclosed |
| US-7432029-B2 | Electrophotographic photoreceptor containing asymmetrical naphthalenetetracarboxylic acid diimide derivatives and electrophotographic imaging apparatus employing the photoreceptor | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2008-10-07 | — | — | US | disclosed |