Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | BRD1 | O95696 | 1/20 | 0.46 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18470153 | 0.92 | MAPT (0.50) | MAPTALDH1A1HSD17B10ESR1KMT2A | |
| SCHEMBL6392226 | 0.87 | SCN2A (0.66) | MAPTALDH1A1HSD17B10ESR1KMT2A | |
| SCHEMBL18475611 | 0.82 | ESR1 (0.44) | MAPTALDH1A1HSD17B10ESR1KMT2A | |
| SCHEMBL14016764 | 0.82 | ESR1 (0.48) | MAPTALDH1A1HSD17B10ESR1KMT2A | |
| SCHEMBL18379166 | 0.80 | STAT3 (0.44) | MAPTALDH1A1HSD17B10ESR1KMT2A | |
| SCHEMBL6005777 | 0.80 | SCN2A (0.72) | MAPTALDH1A1HSD17B10ESR1KMT2A | |
| SCHEMBL10705337 | 0.78 | MGLL (0.61) | MAPTALDH1A1HSD17B10LMNASMN1; SMN2 | |
| SCHEMBL14110195 | 0.76 | ESR1 (0.46) | MAPTALDH1A1HSD17B10ESR1KMT2A | |
| SCHEMBL14016790 | 0.76 | ALDH1A1 (0.51) | MAPTALDH1A1ESR1KMT2AMEN1 | |
| SCHEMBL14016785 | 0.75 | MEN1 (0.46) | MAPTALDH1A1ESR1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10596164-B2 | Anti-clostridium compounds | NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) | 2020-03-24 | — | — | US | disclosed |
| US-20170035750-A1 | NEW ANTI-CLOSTRIDIUM COMPOUNDS | NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETEN SCHAPPELIJK ONDERZOEK TNO (NL) | 2017-02-09 | — | — | US | disclosed |
| US-20170035750-A1 | NEW ANTI-CLOSTRIDIUM COMPOUNDS | NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETEN SCHAPPELIJK ONDERZOEK TNO (NL) | 2017-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10596164-B2 | Anti-clostridium compounds | CLPP, ATP5F1A, ATP5F1C | MAPT 3960/4885ALDH1A1 3578/4885HSD17B10 1502/4885 |
| US-20170035750-A1 | NEW ANTI-CLOSTRIDIUM COMPOUNDS | ANTXR2, CLPP, DAD1 | MAPT 2771/4885ALDH1A1 4153/4885HSD17B10 1171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.