Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | ACACA | Q13085 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 4/20 | 0.39 |
| ▸ | L3MBTL3 | Q96JM7 | 7/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.39 |
| ▸ | MBTD1 | Q05BQ5 | 4/20 | 0.39 |
| ▸ | TP53BP1 | Q12888 | 2/20 | 0.39 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1713072 | 0.88 | ALDH1A1 (0.42) | MEN1KMT2ACHRM1ALDH1A1 | |
| SCHEMBL13772727 | 0.83 | MEN1 (0.58) | MEN1KMT2AACHEL3MBTL3L3MBTL1 | |
| SCHEMBL13772749 | 0.83 | MEN1 (0.58) | MEN1KMT2AACHEL3MBTL3L3MBTL1 | |
| SCHEMBL13772800 | 0.80 | L3MBTL3 (0.43) | MEN1KMT2AACACBACACAACHE | |
| SCHEMBL4720502 | 0.79 | L3MBTL3 (0.42) | MEN1KMT2ACHRM1L3MBTL3L3MBTL1 | |
| SCHEMBL13772828 | 0.78 | KDM4E (0.50) | MEN1KMT2AACHEL3MBTL3L3MBTL1 | |
| SCHEMBL13665501 | 0.76 | DPP4 (0.49) | CHRM1ALDH1A1 | |
| SCHEMBL1712955 | 0.76 | DPP4 (0.49) | CHRM1ALDH1A1 | |
| SCHEMBL13772875 | 0.75 | L3MBTL3 (0.44) | MEN1KMT2AACHEL3MBTL3L3MBTL1 | |
| SCHEMBL8353063 | 0.74 | CHRM1 (0.70) | CHRM1L3MBTL1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863791-B1 | 2-OXO-1,2,4,5-TETRAHYDRO-1,3-BENZODIAZEPIN-3-YL-PIPERIDINES USED AS CGRP ANTAGONISTS | BOEHRINGER INGELHEIM INT (DE) | 2008-11-12 | — | — | EP | disclosed |