Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 9/20 | 0.80 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.80 |
| ▸ | PPARG | P37231 | 2/20 | 0.80 |
| ▸ | FABP2 | P12104 | 1/20 | 0.80 |
| ▸ | PPARD | Q03181 | 1/20 | 0.80 |
| ▸ | ESRRG | P62508 | 5/20 | 0.66 |
| ▸ | ESRRB | O95718 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | GFER | P55789 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22943060 | 0.90 | PPARA (0.80) | PPARASMN1; SMN2ALDH1A1PPARGFABP2 | |
| Bezafibrate SCHEMBL16299 | 0.89 | PPARA (1.00) | PPARASMN1; SMN2ALDH1A1PPARGFABP2 | |
| Bezafibrate SCHEMBL5077755 | 0.89 | PPARA (1.00) | PPARASMN1; SMN2ALDH1A1PPARGFABP2 | |
| Bezafibrate SCHEMBL3088387 | 0.88 | PPARA (0.98) | PPARASMN1; SMN2ALDH1A1PPARGFABP2 | |
| Bezafibrate SCHEMBL22364278 | 0.88 | PPARA (0.98) | PPARASMN1; SMN2ALDH1A1PPARGFABP2 | |
| Bezafibrate SCHEMBL28565716 | 0.88 | PPARA (0.98) | PPARASMN1; SMN2ALDH1A1PPARGFABP2 | |
| SCHEMBL11687764 | 0.87 | PPARA (0.75) | PPARASMN1; SMN2ALDH1A1PPARGFABP2 | |
| SCHEMBL11683879 | 0.86 | PPARA (0.74) | PPARASMN1; SMN2ALDH1A1PPARGFABP2 | |
| Bezafibrate SCHEMBL15156489 | 0.85 | PPARA (0.91) | PPARASMN1; SMN2ALDH1A1PPARGFABP2 | |
| SCHEMBL11509548 | 0.83 | PPARA (0.67) | PPARASMN1; SMN2ALDH1A1PPARGFABP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7439394-B2 | Cyclohexyl-1,4-diamine compounds | GRUENENTHAL GMBH (DE) | 2008-10-21 | — | — | US | disclosed |
| US-7439394-B2 | Cyclohexyl-1,4-diamine compounds | GRUENENTHAL GMBH (DE) | 2008-10-21 | — | — | US | disclosed |
| US-20070117803-A1 | Cyclohexyl-1,4-diamine compounds | GRUENENTHAL GMBH (DE) | 2007-05-24 | — | — | US | disclosed |
| US-20070117803-A1 | Cyclohexyl-1,4-diamine compounds | GRUENENTHAL GMBH (DE) | 2007-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070117803-A1 | Cyclohexyl-1,4-diamine compounds | PKD1, DDC, DPYD | PPARA 3433/4885SMN1; SMN2 1061/4885ALDH1A1 158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.