Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCK | P27707 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.34 |
| ▸ | LDHA | P00338 | 1/20 | 0.34 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23367954 | 0.80 | APP (0.44) | DCKKDM4EADORA1APP | |
| SCHEMBL8331917 | 0.72 | ALDH1A1 (0.38) | KDM4EHSD17B13METTDP1HRH3 | |
| SCHEMBL28414585 | 0.71 | MAPT (0.43) | KDM4ETDP1APP | |
| SCHEMBL5154428 | 0.71 | ALDH1A1 (0.49) | KDM4EADORA2AADORA1 | |
| SCHEMBL12789113 | 0.71 | HDAC1 (0.46) | LDHA | |
| SCHEMBL2684464 | 0.69 | KDM4E (0.52) | KDM4E | |
| SCHEMBL14332762 | 0.69 | ALDH1A1 (0.47) | — | |
| SCHEMBL14240524 | 0.68 | ALDH1A1 (0.46) | DCKKDM4EMAP4K4 | |
| SCHEMBL3703503 | 0.66 | — | — | |
| SCHEMBL380344 | 0.66 | MAP4K4 (0.47) | KDM4EMAP4K4ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343503-B1 | HETEROARYL UREA NEUROPEPTIDE Y Y5 RECEPTOR ANTAGONISTS | SCHERING CORP (US) | 2008-11-12 | — | — | EP | disclosed |
| US-7309704-B2 | Heteroaryl urea neuropeptide Y Y5 receptor antagonists | SCHERING CORPORATION (US) | 2007-12-18 | — | — | US | disclosed |
| US-7309704-B2 | Heteroaryl urea neuropeptide Y Y5 receptor antagonists | SCHERING CORPORATION (US) | 2007-12-18 | — | — | US | disclosed |