Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 10/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27667559 | 0.83 | NOTUM (0.53) | MAPTKDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL23367954 | 0.83 | APP (0.44) | MAPTKDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL5154428 | 0.83 | ALDH1A1 (0.49) | MAPTKDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL2684464 | 0.81 | KDM4E (0.52) | MAPTKDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL20641446 | 0.79 | SNCA (0.56) | MAPTKDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL31219241 | 0.79 | NOS1 (0.48) | MAPTKDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL31341111 | 0.79 | APP (0.44) | APPGAA | |
| SCHEMBL15998127 | 0.78 | NOS1 (0.36) | ALDH1A1HPGD | |
| SCHEMBL15547000 | 0.75 | ALDH1A1 (0.47) | MAPTKDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL31312542 | 0.75 | HSD17B1 (0.53) | MAPTKDM4ENPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111263756-A | RAD51 inhibitors | 赛泰尔治疗公司 | 2020-06-09 | — | — | CN | disclosed |