Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 4/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 5/20 | 0.37 |
| ▸ | RAB9A | P51151 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5743046 | 0.73 | ALDH1A1 (0.47) | ALDH1A1HPGDALOX15SMN1; SMN2CYP1A2 | |
| SCHEMBL8178603 | 0.73 | ALDH1A1 (0.44) | ALDH1A1HPGDALOX15SMN1; SMN2CYP3A4 | |
| SCHEMBL12208069 | 0.71 | ALDH1A1 (0.45) | ALDH1A1HPGDALOX15SMN1; SMN2ATG4B | |
| SCHEMBL12208210 | 0.71 | ATG4B (0.46) | ALDH1A1HPGDALOX15SMN1; SMN2ATG4B | |
| SCHEMBL14018491 | 0.69 | DCK (0.36) | — | |
| SCHEMBL8331917 | 0.69 | ALDH1A1 (0.38) | ALDH1A1CYP1A2MEN1KMT2AMAPT | |
| SCHEMBL13298952 | 0.68 | XDH (0.44) | ALDH1A1HPGDALOX15SMN1; SMN2ATG4B | |
| SCHEMBL12597661 | 0.68 | ATG4B (0.43) | ALDH1A1HPGDALOX15SMN1; SMN2CYP1A2 | |
| SCHEMBL12789113 | 0.68 | HDAC1 (0.46) | ALDH1A1HPGDSMN1; SMN2CYP1A2MAPK9 | |
| SCHEMBL11855456 | 0.67 | ALDH1A1 (0.38) | ALDH1A1HPGDALOX15SMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7309704-B2 | Heteroaryl urea neuropeptide Y Y5 receptor antagonists | SCHERING CORPORATION (US) | 2007-12-18 | — | — | US | disclosed |
| US-7309704-B2 | Heteroaryl urea neuropeptide Y Y5 receptor antagonists | SCHERING CORPORATION (US) | 2007-12-18 | — | — | US | disclosed |