Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 8/20 | 0.53 |
| ▸ | TOP2A | P11388 | 2/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.44 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.44 |
| ▸ | PTPRF | P10586 | 1/20 | 0.44 |
| ▸ | ACP1 | P24666 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | NT5E | P21589 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.43 |
| ▸ | ALB | P02768 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18760924 | 1.00 | PTPN1 (0.53) | PTPN1TOP2ACES2CES1GPBAR1 | |
| SCHEMBL17866956 | 0.83 | GLI1 (0.36) | PTPN1TOP2ACES2CES1GPBAR1 | |
| Tetrahymanol SCHEMBL5831685 | 0.81 | PTPN1 (0.57) | PTPN1TOP2ACES2CES1GPBAR1 | |
| Tetrahymanol SCHEMBL1401904 | 0.81 | PTPN1 (0.57) | PTPN1TOP2ACES2CES1GPBAR1 | |
| SCHEMBL18760925 | 0.73 | PTPN1 (0.43) | PTPN1 | |
| SCHEMBL16431162 | 0.73 | PTPN1 (0.43) | PTPN1 | |
| SCHEMBL18730228 | 0.73 | PTPN1 (0.43) | PTPN1TOP2ACES2CES1GPBAR1 | |
| SCHEMBL30901202 | 0.71 | PTPN1 (0.53) | PTPN1TOP2ACES2CES1GPBAR1 | |
| SCHEMBL17867237 | 0.71 | SLC10A1 (0.55) | PTPN1TOP2ACES2CES1GPBAR1 | |
| SCHEMBL12640552 | 0.71 | PTPN1 (0.61) | PTPN1TOP2ACES2CES1GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190309289-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | ENEVOLV, INC. | 2019-10-10 | — | — | US | disclosed |
| US-10370654-B2 | Processes and host cells for genome, pathway, and biomolecular engineering | ENEVOLV, INC. (US) | 2019-08-06 | — | — | US | disclosed |
| US-20180320170-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | ENEVOLV, INC. | 2018-11-08 | — | — | US | disclosed |
| US-9944925-B2 | Processes and host cells for genome, pathway, and biomolecular engineering | ENEVOLV, INC. | 2018-04-17 | — | — | US | disclosed |
| US-20160186168-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | ENEVOLV, INC. | 2016-06-30 | — | — | US | disclosed |