Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | NPC1 | O15118 | 4/20 | 0.64 |
| ▸ | RAB9A | P51151 | 4/20 | 0.64 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.61 |
| ▸ | RELA | Q04206 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TDO2 | P48775 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | AR | P10275 | 2/20 | 0.47 |
| ▸ | RAC1 | P63000 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14019107 | 0.95 | KDM4E (0.72) | KDM4ESMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL14019147 | 0.89 | MAPT (0.54) | KDM4ESMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL14019146 | 0.83 | MAPT (0.56) | KDM4ESMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL14019148 | 0.82 | TDO2 (0.45) | KDM4ESMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL14981161 | 0.81 | MAPT (0.59) | KDM4ESMN1; SMN2ALDH1A1MAPTHPGD | |
| SCHEMBL14019139 | 0.81 | MAPT (0.53) | KDM4ESMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL14019086 | 0.80 | MAPT (0.64) | SMN1; SMN2ALDH1A1RAB9AMAPTMEN1 | |
| SCHEMBL30702310 | 0.79 | KDM4E (1.00) | KDM4ESMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL14019116 | 0.79 | SMN1; SMN2 (0.61) | KDM4ESMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL14019134 | 0.78 | MAPT (0.56) | KDM4ESMN1; SMN2ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7442447-B2 | Binaphthol based chromophores for the fabrication of blue organic light emitting diodes | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-10-28 | — | — | US | disclosed |
| US-7442447-B2 | Binaphthol based chromophores for the fabrication of blue organic light emitting diodes | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-10-28 | — | — | US | disclosed |