SCHEMBL1401929

SCHEMBL1401929

CC[C@@H]1CC[C@H]2[C@@H]3CCC4=CCCC[C@]4(C)C3=CC[C@]12C

nearest known ligand 0.41

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 18/20 0.40
NR3C1 P04150 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8020260 1.00 CYP19A1 (0.40) CYP19A1NR3C1
SCHEMBL10529663 0.84 CYP19A1 (0.38) CYP19A1NR3C1
SCHEMBL10529661 0.84 CYP19A1 (0.38) CYP19A1NR3C1
SCHEMBL11639279 0.76 CYP19A1 (0.43) CYP19A1NR3C1
SCHEMBL8999955 0.76 CYP19A1 (0.41) CYP19A1NR3C1
SCHEMBL10942965 0.75 CYP19A1 (0.44) CYP19A1
SCHEMBL10942830 0.75 NFKB1 (0.35) CYP19A1
SCHEMBL9470387 0.74 ESR1 (0.46) CYP19A1NR3C1
SCHEMBL8999950 0.74 CYP19A1 (0.70) CYP19A1
SCHEMBL6437116 0.74 CASP1 (0.51) CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100266664-A1 Devices And Methods For Ophthalmic Drug Delivery ALCON RESEARCH, LTD. (US) 2010-10-21 US claimed
EP-1221919-B1 OPHTHALMIC DRUG DELIVERY DEVICE ALCON INC (CH) 2005-02-23 EP claimed
US-5770592-A VISION DEFECTS ALCON LABORATORIES, INC. (US) 1998-06-23 US claimed
EP-3700595-B1 KITS FOR ANCHORING IMPLANTABLE MEDICAL DEVICES MEDTRONIC INC (US) 2024-06-19 EP disclosed
US-11944825-B2 Surgical system and methods of use MEDTRONIC, INC (US) 2024-04-02 US disclosed
EP-3568168-B1 TUBE COVERING FOR AN IMPLANTABLE DEVICE MEDTRONIC INC (US) 2023-11-22 EP disclosed
EP-4274548-A1 SURGICAL SYSTEM AND METHODS OF USE Medtronic, Inc. (US) 2023-11-15 EP disclosed
EP-4274629-A1 SURGICAL SYSTEM AND METHODS OF USE Medtronic, Inc. (US) 2023-11-15 EP disclosed
US-20230173764-A1 SURGICAL SYSTEM AND METHODS OF USE MEDTRONIC INC. (US) 2023-06-08 US disclosed
EP-3452122-B1 HEMOSTATIC DEVICES AND METHODS OF USE MEDTRONIC INC (US) 2023-03-22 EP disclosed
US-20230079760-A1 SURGICAL SYSTEM AND METHODS OF USE MEDTRONIC INC. (US) 2023-03-16 US disclosed
EP-1473003-B1 Drug delivery device ALCON INC (CH) 2008-11-19 EP disclosed
US-20080132922-A1 Mesh Pouches for Implantable Medical Devices TYRX PHARMA, INC. (US) 2008-06-05 US disclosed
US-20080128315-A1 Biodegradable polylactic acid polymer pouches for pacemaker, defibrillator, pulse generator cardiac rhythm mamagent devices; antimicrobial agents, anesthetics, anti-inflammatory agents, anti-scarring drugs in polymer matrix; barrier to microbial colonization of medical device during surgical implantation TYRX PHARMA, INC. (US) 2008-06-05 US disclosed
EP-1888660-A2 BIOCOMPATIBLE POLYMERS AND CO-POLYMERS COMPRISING AMINO ACIDS IN THE SIDE CHAIN Chemisches Institut Schaefer AG (CH) 2008-02-20 EP disclosed
WO-2006126095-A2 BIOCOMPATIBLE POLYMERS AND CO-POLYMERS COMPRISING AMINO ACIDS IN THE SIDE CHAIN CHEMISCHES INSTITUT SCHAEFER AG (CH) 2006-11-30 WO disclosed
EP-1473003-A2 Drug delivery device Alcon, Inc. (CH) 2004-11-03 EP disclosed
US-6413245-B1 Sub-tenon drug delivery ALCON UNIVERSAL LTD. (CH) 2002-07-02 US disclosed
US-6172054-B1 ANGIOSTATIC AGENT ALCON LABORATORIES, INC. 2001-01-09 US disclosed
US-5371078-A Angiostatic steroids and methods and compositions for controlling ocular hypertension ALCON LABORATORIES, INC. (US) 1994-12-06 US disclosed