SCHEMBL8020260

SCHEMBL8020260

CC[C@H]1CC[C@H]2[C@@H]3CCC4=CCCC[C@]4(C)C3=CC[C@]12C

nearest known ligand 0.41

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 18/20 0.40
NR3C1 P04150 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1401929 1.00 CYP19A1 (0.40) CYP19A1NR3C1
SCHEMBL10529663 0.84 CYP19A1 (0.38) CYP19A1NR3C1
SCHEMBL10529661 0.84 CYP19A1 (0.38) CYP19A1NR3C1
SCHEMBL11639279 0.76 CYP19A1 (0.43) CYP19A1NR3C1
SCHEMBL8999955 0.76 CYP19A1 (0.41) CYP19A1NR3C1
SCHEMBL10942965 0.75 CYP19A1 (0.44) CYP19A1
SCHEMBL10942830 0.75 NFKB1 (0.35) CYP19A1
SCHEMBL9470387 0.74 ESR1 (0.46) CYP19A1NR3C1
SCHEMBL8999950 0.74 CYP19A1 (0.70) CYP19A1
SCHEMBL6437116 0.74 CASP1 (0.51) CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12594262-B2 CAI nanoemulsions FORWARDVUE PHARMA, INC. (US) 2026-04-07 US disclosed
US-20250387259-A1 OCULAR IMPLANTS FOR CONTROLLED DRUG RELEASE UNIV CALIFORNIA (US) 2025-12-25 US disclosed
US-12447242-B2 Hemostatic devices and methods of use MEDTRONIC, INC. (US) 2025-10-21 US disclosed
EP-3452124-B1 HEMOSTATIC DEVICES AND METHODS OF USE MEDTRONIC INC (US) 2025-10-08 EP disclosed
EP-3452123-B1 HEMOSTATIC DEVICES AND METHODS OF USE MEDTRONIC INC (US) 2025-09-24 EP disclosed
EP-3452126-B1 HEMOSTATIC DEVICES AND METHODS OF USE MEDTRONIC INC (US) 2025-08-27 EP disclosed
US-20250262358-A1 SURGICAL SYSTEM AND METHODS OF USE MEDTRONIC INC (US) 2025-08-21 US disclosed
EP-3452125-B1 CUSTOMIZABLE ANCHORAGE DEVICES AND METHODS OF USE MEDTRONIC INC (US) 2025-07-16 EP disclosed
US-12168085-B2 Surgical system and methods of use MEDTRONIC, INC (US) 2024-12-17 US disclosed
US-12168086-B2 Hemostatic devices and methods of use MEDTRONIC, INC (US) 2024-12-17 US disclosed
US-5750745-A STEROIDS SCHERING CORPORATION (US) 1998-05-12 US disclosed
US-4619921-A Polyhalogeno-steroids CIBA-GEIGY CORPORATION (US) 1986-10-28 US disclosed
EP-0061416-B1 PROCESS FOR THE PREPARATION OF DELTA 9(11)- AND DELTA 16-21-CHLORO-20-KETO STEROIDS OF THE PREGNANE AND D-HOMOPREGNANE SERIES AND THEIR USE AS INTERMEDIATES FOR THE SYNTHESIS OF HIGHLY EFFECTIVE CORTICOIDS SCHERING AKTIENGESELLSCHAFT (DE) 1985-11-13 EP disclosed
US-4310466-A ANTIINFLAMMATORY STEROIDS SYNTEX (U.S.A.) INC. (US) 1982-01-12 US disclosed
US-4273770-A CORTICOIDS, ANTIINFLAMMATORY AGENTS SYNTEX (U.S.A.) INC. (US) 1981-06-16 US disclosed
US-4263289-A ANTIINFLAMMATORY STEROIDS SYNTEX (U.S.A.) INC. (US) 1981-04-21 US disclosed
EP-0004741-B1 THIO ETIANIC ACID DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL USE SYNTEX (U.S.A.) INC. (US) 1981-01-28 EP disclosed
US-4188385-A ANTIINFLAMMATORY STERIODS SYNTEX (U.S.A.) INC. (US) 1980-02-12 US disclosed
EP-0004741-A2 Thio etianic acid derivatives, their preparation and pharmaceutical use SYNTEX (U.S.A.) INC. (US) 1979-10-17 EP disclosed
US-4088537-A BIOTRANSFORMATION THE UPJOHN COMPANY (US) 1978-05-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12168086-B2 Hemostatic devices and methods of use PLAT, HABP2, F2 CYP19A1 2624/4885NR3C1 4241/4885
US-12594262-B2 CAI nanoemulsions KDR, FLT4, FLT1 CYP19A1 2041/4885NR3C1 4041/4885
US-12168085-B2 Surgical system and methods of use FGB, F2, COL14A1 CYP19A1 1142/4885NR3C1 3249/4885
US-12447242-B2 Hemostatic devices and methods of use HABP2, PLAT, F2 CYP19A1 1877/4885NR3C1 4285/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.