Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3294020 | 0.86 | LMNA (0.47) | MEN1KMT2AALDH1A1HPGDLMNA | |
| SCHEMBL14019666 | 0.84 | CNR2 (0.42) | RXFP1SLC6A2CNR2S1PR1 | |
| SCHEMBL14019665 | 0.84 | TOP1 (0.38) | RXFP1ATMMEN1KMT2AALDH1A1 | |
| SCHEMBL14019671 | 0.83 | BRD4 (0.31) | — | |
| SCHEMBL14019662 | 0.75 | XDH (0.36) | ALDH1A1HPGDLMNAKDM4EHTT | |
| SCHEMBL4030026 | 0.75 | KDM4E (0.42) | ALDH1A1HPGDLMNAKDM4EHTT | |
| SCHEMBL14019664 | 0.74 | NPC1 (0.32) | ATMMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL14019661 | 0.74 | CNR2 (0.35) | ATMALDH1A1HPGDLMNASLC6A2 | |
| SCHEMBL13799088 | 0.74 | KDM4E (0.42) | ALDH1A1HPGDLMNAKDM4EHTT | |
| SCHEMBL1132860 | 0.72 | LMNA (0.46) | RXFP1MEN1KMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080269146-A1 | 4''-Substituted Erythromycin Derivative | GLAXO GROUP LIMITED | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269146-A1 | 4''-Substituted Erythromycin Derivative | MRPL21, CYP3A4, CYP51A1 | RXFP1 2725/4885ATM 4655/4885MEN1 4432/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.