Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 4/20 | 0.40 |
| ▸ | CA12 | O43570 | 5/20 | 0.40 |
| ▸ | CA1 | P00915 | 5/20 | 0.40 |
| ▸ | CA2 | P00918 | 5/20 | 0.40 |
| ▸ | CA9 | Q16790 | 5/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TXN | P10599 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | APP | P05067 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TERT | O14746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14021965 | 0.92 | MAPT (0.35) | NFKB1CA12CA1CA2CA9 | |
| SCHEMBL14585736 | 0.82 | SMN1; SMN2 (0.40) | NFKB1CA12CA1CA2CA9 | |
| SCHEMBL14010037 | 0.80 | CA9 (0.43) | CA12CA1CA2CA9CA14 | |
| SCHEMBL14159580 | 0.78 | CA9 (0.39) | CA12CA1CA2CA9CA14 | |
| SCHEMBL12589917 | 0.78 | NFKB1 (0.36) | NFKB1CA12CA1CA2CA9 | |
| SCHEMBL14004230 | 0.75 | CHAT (0.42) | CA12CA1CA2CA9CA14 | |
| SCHEMBL14013107 | 0.75 | ENPP2 (0.36) | — | |
| SCHEMBL13599507 | 0.73 | NFKB1 (0.38) | NFKB1CA12CA1CA2CA9 | |
| SCHEMBL13599506 | 0.73 | PRMT1 (0.39) | NFKB1CA12CA1CA2CA9 | |
| SCHEMBL13715757 | 0.71 | AURKA (0.34) | NFKB1KDM4EMAPTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080257208-A1 | Mixtures of Fibre Reactive Dyes | DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) | 2008-10-23 | — | — | US | disclosed |