Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 16/20 | 0.43 |
| ▸ | CA12 | O43570 | 15/20 | 0.43 |
| ▸ | CA1 | P00915 | 15/20 | 0.43 |
| ▸ | CA2 | P00918 | 15/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 7/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14159580 | 0.83 | CA9 (0.39) | CA9CA12CA1CA2CA14 | |
| SCHEMBL14021962 | 0.80 | NFKB1 (0.40) | CA9CA12CA1CA2CA14 | |
| SCHEMBL14004223 | 0.78 | CA9 (0.41) | CA9CA12CA1CA2CA14 | |
| SCHEMBL14004228 | 0.77 | CHAT (0.40) | CA9CA12CA1CA2CA14 | |
| SCHEMBL14079899 | 0.76 | CARM1 (0.38) | CA9CA12CA1CA2CA14 | |
| SCHEMBL14021965 | 0.75 | MAPT (0.35) | CA9CA12CA1CA2CA14 | |
| SCHEMBL13998604 | 0.75 | ENPP2 (0.35) | CA9CA12CA1CA2CA14 | |
| SCHEMBL12052474 | 0.75 | CA12 (0.41) | CA9CA12CA1CA2CA14 | |
| SCHEMBL14079923 | 0.74 | CA9 (0.47) | CA9CA12CA1CA2CA14 | |
| SCHEMBL21239133 | 0.74 | CHAT (0.45) | CA9CA12CA1CA2CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080289123-A1 | Reactive Dyes, Their Preparation and Their Use | HUNTSMAN INTERNATIONAL LLC (US) | 2008-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080289123-A1 | Reactive Dyes, Their Preparation and Their Use | IK, CUTA, CD68 | CA9 370/4885CA12 2083/4885CA1 3942/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.