SCHEMBL1402200

SCHEMBL1402200

CC(C)Cc1ccc(O)cc1O

nearest known ligand 0.59

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TYR P14679 6/20 0.58
GABRA1 P14867 2/20 0.52
GABRB2 P47870 2/20 0.52
ALOX5 P09917 2/20 0.48
MEN1 O00255 2/20 0.48
MAPT P10636 2/20 0.48
KMT2A Q03164 2/20 0.48
TP53 P04637 1/20 0.48
CYP3A4 P08684 1/20 0.48
ALOX15 P16050 1/20 0.48
TSHR P16473 1/20 0.48
HTT P42858 1/20 0.48
TDP1 Q9NUW8 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30386846 0.85 TYR (0.67) TYRALOX5MEN1MAPTKMT2A
SCHEMBL3197381 0.85 TYR (0.67) TYRALOX5MEN1MAPTKMT2A
SCHEMBL9734205 0.84 GABRA1 (0.50) TYRGABRA1GABRB2
SCHEMBL14983869 0.83 TYR (0.46) TYRGABRA1GABRB2ALOX5MEN1
SCHEMBL14478262 0.83 TYR (0.55) TYR
SCHEMBL3138811 0.83 TYR (0.55) TYR
SCHEMBL5877825 0.83 GABRA1 (0.68) TYRGABRA1GABRB2ALOX5MEN1
SCHEMBL2292664 0.81 GABRA1 (0.71) GABRA1GABRB2ALOX5MEN1MAPT
SCHEMBL21503461 0.81 GABRA1 (0.50) TYRGABRA1GABRB2
SCHEMBL3953639 0.81 TRPA1 (0.50) TYRGABRA1GABRB2MEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 143 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118184498-A Supermolecule resorcinol-licochalcone A-ion salt and preparation method and application thereof 百特威(上海)化妆品有限公司 2024-06-14 CN claimed
CN-116867474-A Double-layer cosmetic 株式会社资生堂 2023-10-10 CN claimed
CN-115919671-A Anti-aging freeze-dried mask beneficial to storage 常州伟博海泰化妆品有限公司 2023-04-07 CN claimed
WO-2022196480-A1 DOUBLE-LAYER COSMETIC 株式会社 資生堂 2022-09-22 WO claimed
CN-115006279-A Clathrate compound and preparation method thereof, external preparation and preparation method thereof 沈阳药科大学 2022-09-06 CN claimed
EP-2292208-B1 EXTERNAL PREPARATION FOR SKIN SHISEIDO CO LTD (JP) 2017-07-19 EP claimed
US-9101564-B2 Heparanase activity inhibitor, wrinkle improving agent containing same, and pharmaceutical composition SHISEIDO COMPANY, LTD. (JP) 2015-08-11 US claimed
US-8486997-B2 External preparation for skin SHISEIDO COMPANY (JP) 2013-07-16 US claimed
EP-2484349-A1 HEPARANASE-ACTIVITY INHIBITOR, WRINKLE AMELIORATING AGENT CONTAINING SAME, AND PHARMACEUTICAL COMPOSITION Shiseido Co., Ltd. (JP) 2012-08-08 EP claimed
US-20120184782-A1 HEPARANASE ACTIVITY INHIBITOR, WRINKLE IMPROVING AGENT CONTAINING SAME, AND PHARMACEUTICAL COMPOSITION SHISEIDO COMPANY, LTD. 2012-07-19 US claimed
US-20110213030-A1 External Preparation For Skin SHISEIDO COMPANY, LTD. (JP) 2011-09-01 US claimed
EP-2292208-A1 EXTERNAL PREPARATION FOR SKIN Shiseido Company, Ltd. (JP) 2011-03-09 EP claimed
US-4487975-A Etherification of phenols RHONE-POULENC INDUSTRIES (FR) 1984-12-11 US claimed
CN-118265517-A Oil-in-water type emulsified cosmetic 株式会社资生堂 2024-06-28 CN disclosed
CN-118184498-A Supermolecule resorcinol-licochalcone A-ion salt and preparation method and application thereof 百特威(上海)化妆品有限公司 2024-06-14 CN disclosed
CN-116867474-A Double-layer cosmetic 株式会社资生堂 2023-10-10 CN disclosed
EP-0277907-A2 Low temperature synthesis of condensation polymers SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1988-08-10 EP disclosed
US-4668762-A OXYGEN-SILICON-PHOSPHORUS-CONTAINING COMPOUNDS, ACID ACCEPTORS AND HALO COMPOUND TO MAKE POLYESTERS,-UREAS AND AMIDES AT LOW TEMPERATURE THE GOODYEAR TIRE & RUBBER COMPANY (US) 1987-05-26 US disclosed
US-4487975-A Etherification of phenols RHONE-POULENC INDUSTRIES (FR) 1984-12-11 US disclosed
US-4225619-A BACTERICIDES, FUNGICIDES BOEHRINGER INGELHEIM GMBH (DE) 1980-09-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120184782-A1 HEPARANASE ACTIVITY INHIBITOR, WRINKLE IMPROVING AGENT CONTAINING SAME, AND PHARMACEUTICAL COMPOSITION HPSE, MMP7, COLGALT1 TYR 1311/4885GABRA1 4368/4885GABRB2 4369/4885
US-20110213030-A1 External Preparation For Skin CYP46A1, PROC, CYP24A1 TYR 686/4885GABRA1 4544/4885GABRB2 4409/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.