Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.63 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.63 |
| ▸ | RAF1 | P04049 | 6/20 | 0.62 |
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.60 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.60 |
| ▸ | PDE4A | P27815 | 1/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.60 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.60 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.60 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.60 |
| ▸ | KDR | P35968 | 3/20 | 0.60 |
| ▸ | BRAF | P15056 | 1/20 | 0.60 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.60 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14022019 | 0.88 | RAF1 (0.58) | EPHX2RAF1LMNAMEN1KMT2A | |
| SCHEMBL11008724 | 0.87 | EPHX1 (0.81) | EPHX1EPHX2RAF1LMNAMEN1 | |
| SCHEMBL15574278 | 0.86 | RAB9A (0.62) | LMNAHTTNPC1MAPTMAPK1 | |
| SCHEMBL936533 | 0.84 | RAF1 (0.73) | EPHX2RAF1MEN1KMT2AADORA3 | |
| SCHEMBL30462521 | 0.84 | RAF1 (0.73) | EPHX2RAF1MEN1KMT2AADORA3 | |
| SCHEMBL14022021 | 0.83 | RAF1 (0.56) | RAF1LMNAMEN1KMT2AHTT | |
| SCHEMBL29045853 | 0.82 | RAF1 (0.70) | EPHX2RAF1MEN1KMT2AADORA3 | |
| SCHEMBL14067061 | 0.81 | KDR (0.61) | EPHX2RAF1MEN1KMT2ANPC1 | |
| SCHEMBL28863218 | 0.80 | CDK8 (0.83) | EPHX1EPHX2CA12CA1CA2 | |
| SCHEMBL18037977 | 0.80 | LMNA (0.56) | EPHX1EPHX2RAF1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080269265-A1 | Inhibition Of Raf Kinase Using Symmetrical And Unsymmetrical Substituted Diphenyl Ureas | MILLER SCOTT | 2008-10-30 | — | — | US | disclosed |
| US-20080269265-A1 | Inhibition Of Raf Kinase Using Symmetrical And Unsymmetrical Substituted Diphenyl Ureas | MILLER SCOTT | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269265-A1 | Inhibition Of Raf Kinase Using Symmetrical And Unsymmetrical Substituted Diphenyl Ureas | BRAF, RAF1, MAP2K2 | EPHX1 2555/4885EPHX2 1842/4885RAF1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.