SCHEMBL14022232

SCHEMBL14022232

CCC1CC2CCCC(Cn3cnc4c(Cl)ncnc43)(C1)C2

nearest known ligand 0.37

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
FGFR1 P11362 8/20 0.37
FGFR4 P22455 8/20 0.37
FDPS P14324 1/20 0.36
METTL3 Q86U44 1/20 0.35
METTL14 Q9HCE5 1/20 0.35
P2RX7 Q99572 2/20 0.35
HDAC6 Q9UBN7 1/20 0.33
ADORA2A P29274 1/20 0.33
ADORA2B P29275 1/20 0.33
ADORA1 P30542 1/20 0.33
DGAT1 O75907 1/20 0.32
TLR7 Q9NYK1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4751440 0.79 CYP11B1 (0.47) FGFR1FGFR4FDPSMETTL3METTL14
SCHEMBL4752076 0.73 FDPS (0.43) FGFR1FGFR4FDPSP2RX7HDAC6
SCHEMBL21138186 0.72 TP53 (0.31)
SCHEMBL23436498 0.67 ADORA2A (0.66) FGFR1FGFR4FDPSP2RX7HDAC6
SCHEMBL7832523 0.67 ADORA2A (0.64) FGFR1FGFR4FDPSP2RX7HDAC6
SCHEMBL11596393 0.66 FDPS (0.54) FGFR1FGFR4FDPSP2RX7HDAC6
SCHEMBL4751437 0.65 CYP11B1 (0.47) METTL3METTL14P2RX7ADORA2AADORA1
SCHEMBL8982987 0.65 ADORA2A (0.68) FGFR1FGFR4FDPSP2RX7HDAC6
SCHEMBL31331791 0.65 ADORA2A (0.68) FGFR1FGFR4FDPSP2RX7HDAC6
SCHEMBL11596860 0.64 FDPS (0.52) FGFR1FGFR4FDPSP2RX7HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008131502-A2 ANTIVIRAL COMPOUNDS OF THE ADAMANTANE TYPE KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2008-11-06 WO disclosed