Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.47 |
| ▸ | PI4KA | P42356 | 2/20 | 0.41 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.41 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.41 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.41 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.38 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4751440 | 0.83 | CYP11B1 (0.47) | CYP11B1CYP11B2PI4KAPI4K2BPI4K2A | |
| SCHEMBL4748512 | 0.73 | HPRT1 (0.51) | CYP11B1CYP11B2 | |
| SCHEMBL4748530 | 0.71 | CYP11B1 (0.46) | CYP11B1CYP11B2CNR2P2RX7 | |
| SCHEMBL6013391 | 0.71 | ADORA2A (0.64) | PI4KAPI4K2BPI4K2API4KBADORA1 | |
| SCHEMBL4752076 | 0.70 | FDPS (0.43) | CYP11B1CYP11B2PI4KAPI4K2BPI4K2A | |
| SCHEMBL455646 | 0.70 | P2RX7 (0.49) | PI4KAPI4K2BPI4K2API4KBADORA1 | |
| SCHEMBL10889158 | 0.69 | ADORA2A (0.68) | PI4KAPI4K2BPI4K2API4KBADORA1 | |
| SCHEMBL6268495 | 0.68 | PNP (0.53) | — | |
| Hydrochloric Acid SCHEMBL17186583 | 0.67 | PNP (0.52) | — | |
| SCHEMBL28191737 | 0.66 | ADORA2A (0.34) | PI4KAPI4K2BPI4K2API4KBADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008131502-A2 | ANTIVIRAL COMPOUNDS OF THE ADAMANTANE TYPE | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2008-11-06 | — | — | WO | disclosed |