Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 8/20 | 0.41 |
| ▸ | FGFR4 | P22455 | 8/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | PI4KA | P42356 | 1/20 | 0.39 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.39 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4751440 | 0.86 | CYP11B1 (0.47) | FDPSP2RX7FGFR1FGFR4HDAC6 | |
| SCHEMBL4750901 | 0.83 | P2RX7 (0.41) | P2RX7HDAC6CYP11B1CYP11B2 | |
| SCHEMBL11596393 | 0.74 | FDPS (0.54) | FDPSP2RX7FGFR1FGFR4HDAC6 | |
| SCHEMBL4750863 | 0.73 | PI4KA (0.69) | FDPSP2RX7FGFR1FGFR4HDAC6 | |
| SCHEMBL11596726 | 0.73 | ADORA2A (0.68) | FDPSP2RX7FGFR1FGFR4HDAC6 | |
| SCHEMBL14022232 | 0.73 | FGFR1 (0.37) | FDPSP2RX7FGFR1FGFR4HDAC6 | |
| SCHEMBL23436498 | 0.72 | ADORA2A (0.66) | FDPSP2RX7FGFR1FGFR4HDAC6 | |
| SCHEMBL9741153 | 0.72 | ADORA2A (0.66) | FDPSP2RX7FGFR1FGFR4HDAC6 | |
| SCHEMBL11596860 | 0.72 | FDPS (0.52) | FDPSP2RX7FGFR1FGFR4HDAC6 | |
| SCHEMBL15453238 | 0.72 | FDPS (0.52) | FDPSP2RX7FGFR1FGFR4HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008131502-A2 | ANTIVIRAL COMPOUNDS OF THE ADAMANTANE TYPE | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2008-11-06 | — | — | WO | claimed |
| WO-2008131502-A2 | ANTIVIRAL COMPOUNDS OF THE ADAMANTANE TYPE | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2008-11-06 | — | — | WO | disclosed |