Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14022031 | 1.00 | LMNA (0.47) | LMNAPOLBL3MBTL1TDP1MEN1 | |
| SCHEMBL14022033 | 0.85 | LMNA (0.65) | LMNAMEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL14022030 | 0.77 | POLB (0.49) | LMNAPOLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4749352 | 0.77 | POLB (0.49) | LMNAPOLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2989944 | 0.74 | POLB (0.63) | LMNAPOLBKMT2ASMN1; SMN2HPGD | |
| SCHEMBL12468478 | 0.73 | POLB (0.57) | LMNAPOLBMEN1KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL30124838 | 0.69 | POLB (0.66) | LMNAPOLBL3MBTL1TDP1MEN1 | |
| SCHEMBL28911206 | 0.68 | MEN1 (0.56) | LMNAPOLBL3MBTL1MEN1KMT2A | |
| SCHEMBL9678933 | 0.68 | KMT2A (0.63) | LMNATDP1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9678585 | 0.68 | KMT2A (0.63) | LMNATDP1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008135386-A1 | CHIRAL LIGANDS OF THE N-HETEROCYCLIC CARBENE TYPE FOR ASYMMETRICAL CATALYSIS | ECOLE NATIONALE SUPERIEURE DE CHIMIE DE RENNES (FR) | 2008-11-13 | — | — | WO | disclosed |