Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | PKM | P14618 | 3/20 | 0.50 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14022031 | 0.85 | LMNA (0.47) | LMNASMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL14022792 | 0.85 | LMNA (0.47) | LMNASMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL9680727 | 0.84 | SMN1; SMN2 (0.60) | LMNASMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL15637303 | 0.76 | SMN1; SMN2 (0.58) | LMNASMN1; SMN2HPGDKMT2ALPAR1 | |
| SCHEMBL14022673 | 0.76 | HPGD (0.56) | LMNASMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL9681089 | 0.70 | KMT2A (0.57) | LMNASMN1; SMN2HPGDMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL30175716 | 0.68 | SCN1A (0.54) | LMNAMEN1KMT2APKMALDH1A1 | |
| SCHEMBL10243312 | 0.68 | L3MBTL1 (0.48) | LMNASMN1; SMN2HPGDLPAR1 | |
| SCHEMBL30824617 | 0.68 | SMN1; SMN2 (0.53) | SMN1; SMN2HPGDMEN1KMT2APKM | |
| SCHEMBL10244994 | 0.67 | CA1 (0.53) | LMNASMN1; SMN2HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008135386-A1 | CHIRAL LIGANDS OF THE N-HETEROCYCLIC CARBENE TYPE FOR ASYMMETRICAL CATALYSIS | ECOLE NATIONALE SUPERIEURE DE CHIMIE DE RENNES (FR) | 2008-11-13 | — | — | WO | disclosed |