Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.33 |
| ▸ | FDPS | P14324 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14023216 | 0.72 | GPR84 (0.32) | GPR84 | |
| SCHEMBL28032777 | 0.64 | CA1 (0.59) | CA1ACE2FFAR1FFAR4GPR84 | |
| SCHEMBL15338395 | 0.64 | CA1 (0.59) | CA1ACE2FFAR1FFAR4GPR84 | |
| SCHEMBL18631730 | 0.64 | CA1 (0.59) | CA1ACE2FFAR1FFAR4GPR84 | |
| SCHEMBL3231557 | 0.63 | CA1 (0.71) | CA1ACE2FFAR1FFAR4GPR84 | |
| SCHEMBL4350645 | 0.63 | CA1 (0.71) | CA1ACE2FFAR1FFAR4GPR84 | |
| SCHEMBL3218364 | 0.63 | CA1 (0.71) | CA1ACE2FFAR1FFAR4GPR84 | |
| SCHEMBL3211014 | 0.63 | CA1 (0.71) | CA1ACE2FFAR1FFAR4GPR84 | |
| SCHEMBL1321582 | 0.63 | CA1 (0.71) | CA1ACE2FFAR1FFAR4GPR84 | |
| SCHEMBL2710871 | 0.63 | CA1 (0.71) | CA1ACE2FFAR1FFAR4GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080262070-A1 | Pharmaceutically Active Tetrahydro-Pyrrolizinone Compounds | BAUMANN KARL | 2008-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080262070-A1 | Pharmaceutically Active Tetrahydro-Pyrrolizinone Compounds | VCAM1, ICAM1, EPCAM | CA1 3533/4885ACE2 2047/4885FFAR1 618/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.