Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.31 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11892711 | 0.79 | L3MBTL1 (0.36) | L3MBTL1POLBMEN1KMT2ATDP1 | |
| SCHEMBL22230898 | 0.77 | FFAR3 (0.30) | — | |
| SCHEMBL22230897 | 0.77 | FFAR3 (0.30) | — | |
| SCHEMBL4259095 | 0.77 | FFAR3 (0.30) | — | |
| SCHEMBL12224198 | 0.74 | L3MBTL1 (0.39) | L3MBTL1POLBMEN1KMT2ATDP1 | |
| SCHEMBL30067752 | 0.72 | — | — | |
| SCHEMBL10484687 | 0.71 | L3MBTL1 (0.33) | L3MBTL1MEN1KMT2ATDP1CHRNB2 | |
| SCHEMBL19647328 | 0.71 | MGLL (0.44) | — | |
| SCHEMBL11963181 | 0.69 | GRIN2B (0.41) | MEN1KMT2A | |
| SCHEMBL8344035 | 0.69 | GRIN2B (0.41) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008143729-A2 | MACROLIDE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | RIB-X PHARMACEUTICALS, INC. (US) | 2008-11-27 | — | — | WO | disclosed |