Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 17/20 | 0.60 |
| ▸ | OPRD1 | P41143 | 13/20 | 0.60 |
| ▸ | OPRK1 | P41145 | 13/20 | 0.60 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.57 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.57 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.57 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.57 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.57 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.57 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.57 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.48 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13285401 | 0.87 | OPRM1 (0.60) | OPRM1OPRD1OPRK1GRIN2DGRIN3B | |
| SCHEMBL3690702 | 0.84 | OPRM1 (0.67) | OPRM1OPRD1OPRK1GRIN2DGRIN3B | |
| SCHEMBL3692035 | 0.84 | OPRM1 (0.67) | OPRM1OPRD1OPRK1GRIN2DGRIN3B | |
| SCHEMBL3695960 | 0.83 | OPRM1 (0.68) | OPRM1OPRD1OPRK1GRIN2DGRIN3B | |
| SCHEMBL3693707 | 0.83 | OPRM1 (0.71) | OPRM1OPRD1OPRK1GRIN2DGRIN3B | |
| SCHEMBL3690340 | 0.83 | OPRM1 (0.71) | OPRM1OPRD1OPRK1GRIN2DGRIN3B | |
| SCHEMBL3696221 | 0.82 | OPRM1 (0.66) | OPRM1OPRD1OPRK1GRIN2DGRIN3B | |
| SCHEMBL3698837 | 0.81 | OPRM1 (0.64) | OPRM1OPRD1OPRK1GRIN2DGRIN3B | |
| SCHEMBL3699151 | 0.80 | OPRM1 (0.62) | OPRM1OPRD1OPRK1GRIN2DGRIN3B | |
| SCHEMBL12018652 | 0.80 | OPRM1 (0.47) | OPRM1OPRD1OPRK1LPAR1LPAR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080269296-A1 | DIARYL ETHERS AS OPIOID RECEPTOR ANTAGONISTS | BLANCO-PILLADO MARIA-JESUS | 2008-10-30 | — | — | US | disclosed |
| US-20080269296-A1 | DIARYL ETHERS AS OPIOID RECEPTOR ANTAGONISTS | BLANCO-PILLADO MARIA-JESUS | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269296-A1 | DIARYL ETHERS AS OPIOID RECEPTOR ANTAGONISTS | OPRM1, OPRD1, OPRL1 | OPRM1 1/4885OPRD1 2/4885OPRK1 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.