Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 3/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 14/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 11/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 10/20 | 0.48 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14026654 | 0.93 | NNMT (0.50) | NNMTOPRM1OPRK1OPRD1GRIN2D | |
| SCHEMBL14026648 | 0.90 | OPRM1 (0.48) | NNMTOPRM1OPRK1OPRD1GRIN2D | |
| SCHEMBL13242174 | 0.88 | OPRM1 (0.50) | NNMTOPRM1OPRK1OPRD1GRIN2D | |
| SCHEMBL2987688 | 0.85 | OPRM1 (0.47) | NNMTOPRM1OPRK1OPRD1GRIN2D | |
| SCHEMBL2986485 | 0.85 | OPRM1 (0.47) | NNMTOPRM1OPRK1OPRD1LMNA | |
| SCHEMBL2997226 | 0.84 | OPRM1 (0.48) | NNMTOPRM1OPRK1OPRD1GRIN2D | |
| SCHEMBL2994101 | 0.83 | OPRM1 (0.67) | OPRM1OPRK1OPRD1GRIN2DGRIN3B | |
| SCHEMBL2993935 | 0.83 | OPRM1 (0.49) | OPRM1OPRK1OPRD1 | |
| SCHEMBL2987597 | 0.83 | OPRM1 (0.44) | NNMTOPRM1OPRK1OPRD1KCNH2 | |
| SCHEMBL2990579 | 0.83 | OPRM1 (0.49) | OPRM1OPRK1OPRD1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008142454-A1 | BICYCLIC ARYL AND HETEROARYL COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2008-11-27 | — | — | WO | disclosed |