SCHEMBL14026656

SCHEMBL14026656

CCCOC(CC)CCC

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 1/20 0.33
PRKCA P17252 1/20 0.32
PRKCD Q05655 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3016380 0.88 DNM1 (0.36) DNM1
SCHEMBL3723189 0.87 PRKCA (0.36) DNM1PRKCAPRKCD
SCHEMBL27255916 0.85 HSD17B10 (0.33) PRKCAPRKCD
SCHEMBL12250249 0.85
SCHEMBL27733389 0.84 DNM1 (0.40) DNM1PRKCAPRKCD
SCHEMBL8202515 0.84 DNM1 (0.45) DNM1
SCHEMBL22919271 0.84 PRKCA (0.33) DNM1PRKCAPRKCD
SCHEMBL13326798 0.84 DNM1 (0.45) DNM1
SCHEMBL7965352 0.82 PRKCA (0.33) DNM1PRKCAPRKCD
SCHEMBL10375800 0.82 ALDH1A1 (0.35) DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114671834-A Synthesis method of gem-dibromo alkenyl dihydrofuran compound 华南理工大学 2022-06-28 CN disclosed
WO-2008142454-A1 BICYCLIC ARYL AND HETEROARYL COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS PROSIDION LIMITED (GB) 2008-11-27 WO disclosed