SCHEMBL1402676

SCHEMBL1402676

Fc1cccc([S])c1F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride SCHEMBL946295 0.97 CES2 (0.41)
Hydrochloric Acid SCHEMBL942745 0.95 CES2 (0.39)
SCHEMBL180426 0.77
SCHEMBL513579 0.75
Magnesium SCHEMBL6436089 0.74 CES2 (0.50)
SCHEMBL15271850 0.74 CES2 (0.50)
SCHEMBL1402428 0.73 CES2 (0.40)
Fluoride SCHEMBL942752 0.73 ACHE (0.41)
Fluoride SCHEMBL942755 0.73 ACHE (0.41)
Fluoride SCHEMBL944541 0.73 ACHE (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230312471-A1 CHEMICAL PROBES AND INHIBITORS FOR POLYPEPTIDES OF SARS CORONAVIRUSES Universität Konstanz (DE) 2023-10-05 US claimed
EP-4204089-A1 CHEMICAL PROBES AND INHIBITORS FOR POLYPEPTIDES OF SARS CORONAVIRUSES Universität Konstanz (DE) 2023-07-05 EP claimed
JP-2004531514-A 2004-10-14 JP claimed
EP-1381369-A1 USE OF SELECTIVE COX-2 INHIBITORS FOR THE TREATMENT OF URINARY INCONTINENCE RECORDATI INDUSTRIA CHIMICA E FARMACEUTICA S.p.a. (IT) 2004-01-21 EP claimed
WO-2002080927-A1 USE OF SELECTIVE COX-2 INHIBITORS FOR THE TREATMENT OF URINARY INCONTINENCE RECORDATI INDUSTRIA CHIMICA E FARMACEUTICA SPA (IT) 2002-10-17 WO claimed
US-6440963-B1 Use of selective COX-2 inhibitors for the treatment of urinary incontinence RECORDATI S.A., CHEMICAL AND PHARMACEUTICAL COMPANY (CH) 2002-08-27 US claimed
US-20230312471-A1 CHEMICAL PROBES AND INHIBITORS FOR POLYPEPTIDES OF SARS CORONAVIRUSES Universität Konstanz (DE) 2023-10-05 US disclosed
EP-4204089-A1 CHEMICAL PROBES AND INHIBITORS FOR POLYPEPTIDES OF SARS CORONAVIRUSES Universität Konstanz (DE) 2023-07-05 EP disclosed
EP-2123695-B1 METAL THIETANE COMPOUND, POLYMERIZABLE COMPOSITION COMPRISING THE COMPOUND, RESIN, AND USE OF THE RESIN MITSUI CHEMICALS INC (JP) 2021-06-23 EP disclosed
CN-106459523-B The manufacturing method of resin combination, cross-linking agent and cross-linking agent 住友化学株式会社 2019-11-19 CN disclosed
US-9963451-B2 Fused ring pyrimidine compound and pest control agent containing the same MITSUI CHEMICALS AGRO, INC. (JP) 2018-05-08 US disclosed
EP-2314637-B1 COMPOSITION, POLYMERIZABLE COMPOSITION, RESIN, OPTICAL COMPONENT, AND PRODUCTION METHOD OF COMPOSITION MITSUI CHEMICALS INC (JP) 2017-07-12 EP disclosed
US-9635857-B2 Tetrazolinone compound and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-05-02 US disclosed
US-5272163-A Therapeutic amides IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1993-12-21 US disclosed
EP-0524781-A1 Therapeutic amides ZENECA LIMITED (GB) 1993-01-27 EP disclosed
US-4728646-A ANTITHROMBOTICS DR. KARL THOMAE GMBH (DE) 1988-03-01 US disclosed
US-4690923-A ANTITHROMBOTICS KARL THOMAE GMBH (DE) 1987-09-01 US disclosed
US-4518596-A Antithrombotic use of 2-(perhydro-1,4-diazino)-pyrimido (5,4,D)-pyrimidines DR. KARL THOMAE GMBH (DE) 1985-05-21 US disclosed
EP-0023559-B1 2-(PERHYDRO-1,4-DIAZINO)-PYRIMIDO(5,4-D)PYRIMIDINES, THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM Dr. Karl Thomae GmbH (DE) 1984-09-19 EP disclosed
EP-0023559-A1 2-(Perhydro-1,4-diazino)-pyrimido(5,4-d)pyrimidines, their preparation and medicaments containing them Dr. Karl Thomae GmbH (DE) 1981-02-11 EP disclosed