Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | MMP14 | P50281 | 1/20 | 0.44 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.31 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.31 |
| ▸ | S100B | P04271 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4949096 | 0.84 | CYP3A4 (0.52) | CYP3A4MMP9MMP8MMP14ALDH1A1 | |
| SCHEMBL11697335 | 0.80 | PPARG (0.46) | CYP3A4MMP9MMP8MMP14ALDH1A1 | |
| SCHEMBL14028555 | 0.79 | CYP3A4 (0.47) | CYP3A4MMP9MMP8MMP14ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL4951611 | 0.79 | SKP2 (0.57) | CYP3A4MMP9MMP8MMP14SKP2 | |
| SCHEMBL11669127 | 0.79 | SKP2 (0.44) | CYP3A4SKP2ALDH1A1ABL1TSHR | |
| SCHEMBL4953745 | 0.77 | MMP9 (0.46) | CYP3A4MMP9MMP8MMP14ALDH1A1 | |
| SCHEMBL14046454 | 0.76 | MMP9 (0.48) | CYP3A4MMP9MMP8MMP14ALDH1A1 | |
| SCHEMBL205604 | 0.75 | ABL1 (0.56) | CYP3A4SKP2ALDH1A1ABL1TSHR | |
| SCHEMBL10406890 | 0.75 | ABL1 (0.56) | CYP3A4SKP2ALDH1A1ABL1TSHR | |
| SCHEMBL14028551 | 0.75 | ALDH1A1 (0.44) | CYP3A4SKP2ALDH1A1ABL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7435267-B2 | Secondary para-phenylenediamines bearing an alkoxy group, dye composition comprising them, processes therefor and uses thereof | L'OREAL S.A. (FR) | 2008-10-14 | — | — | US | disclosed |
| US-7435267-B2 | Secondary para-phenylenediamines bearing an alkoxy group, dye composition comprising them, processes therefor and uses thereof | L'OREAL S.A. (FR) | 2008-10-14 | — | — | US | disclosed |